Which statement best describes the underlying cause of peptic ulcer disease?

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NCLEX Questions on Gastrointestinal System Questions

Question 1 of 5

Which statement best describes the underlying cause of peptic ulcer disease?

Correct Answer: A

Rationale: The correct answer is A because peptic ulcer disease is primarily caused by the erosion of the gastrointestinal lining due to an imbalance between gastric acid and pepsin. Gastric acid and pepsin can damage the protective lining of the stomach and duodenum, leading to ulcer formation. This process is known as the acid-pepsin hypothesis. Choices B, C, and D are incorrect because they do not directly relate to the underlying cause of peptic ulcer disease. Inflammation of the esophagus due to acid reflux (choice B) is a characteristic of gastroesophageal reflux disease, not peptic ulcer disease. Overproduction of insulin leading to low blood glucose levels (choice C) is a characteristic of hypoglycemia, not peptic ulcer disease. Blockage of the pancreatic ducts leading to digestion of pancreatic tissue (choice D) is a characteristic of pancreatitis, not peptic ulcer disease.

Question 2 of 5

The diagram below represents a process that occurs in organisms. A Broken down to B. Which row in the chart indicates what A and B in the boxes could represent?

Correct Answer: C

Rationale: Step 1: A broken down to B represents the breakdown of proteins into amino acids. Step 2: Proteins are made up of amino acids. Step 3: Therefore, A represents proteins and B represents amino acids. Summary: Choice A is incorrect as starch does not break down into proteins. Choice B is incorrect as starch breaks down into simple sugars, not amino acids. Choice D is incorrect as proteins do not break down into simple sugars.

Question 3 of 5

Where does food pass through between the mouth and the stomach?

Correct Answer: A

Rationale: The correct answer is A: The gullet. Food passes through the gullet, also known as the esophagus, between the mouth and the stomach. The gullet is a muscular tube that contracts to push the food down to the stomach for digestion. The other choices are incorrect because the rectum is where waste is stored before elimination, the small intestine is where most of the absorption of nutrients occurs, and the large intestine is where water is absorbed and waste is further processed before excretion.

Question 4 of 5

What is a function of the secretions produced by structure X?

Correct Answer: A

Rationale: The correct answer is A because the function of structure X's secretions is to increase the surface area of fats for better digestion and absorption in the small intestine. This is achieved by emulsifying fats into smaller droplets, aiding in their breakdown by lipase enzymes. Choices B, C, and D are incorrect as structure X is not involved in stomach acid secretion to decrease pH, protein digestion to peptides, or glycogen breakdown to maltose. The primary role of structure X is related to fat digestion, making choice A the most suitable option.

Question 5 of 5

Trypsin functions best in which of the following conditions?

Correct Answer: A

Rationale: The correct answer is A: basic. Trypsin is a protease enzyme that functions best in basic conditions, specifically at a pH around 8. This is because its active site contains amino acid residues that are positively charged at basic pH, facilitating substrate binding and catalysis. In acidic conditions (choice B), the active site residues may become protonated and lose their positive charge, leading to decreased enzyme activity. Neutral conditions (choice C) are suboptimal for trypsin as it requires basic pH for optimal function. Low pH (choice D) is also not ideal for trypsin as it can denature the enzyme and hinder its catalytic activity.

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