Which of the following is not typically a symptom of autoimmune hemolytic anemia?

Correct Answer: A

Rationale: The correct answer is A: Easy bruising. Autoimmune hemolytic anemia is characterized by the destruction of red blood cells by the immune system, leading to symptoms such as fatigue, mild jaundice, and spleen enlargement. Easy bruising is not a typical symptom of autoimmune hemolytic anemia because it is primarily related to platelet disorders or clotting abnormalities, not red blood cell destruction. Therefore, easy bruising is not directly associated with this specific type of anemia.

Correct Answer: C

Rationale: The correct answer is C: Intestinal polyps. Intestinal polyps can cause long-term blood loss without noticeable symptoms because the blood loss is gradual and may not be enough to cause visible signs like anemia. Bleeding from the kidneys (A), heavy menstrual bleeding (B), and a ruptured blood vessel (D) are more likely to cause noticeable symptoms such as blood in urine, excessive menstrual bleeding, and sudden severe bleeding, respectively.

Correct Answer: C

Rationale: The correct answer is C: Pancytopenia. Pancytopenia refers to a reduction in all three major blood cell types (red blood cells, white blood cells, and platelets). In the given scenario where the entire CBC is suppressed due to anemia, infection, or hemorrhage, it signifies a decrease in all blood cell types. A: Erythroplasia specifically refers to abnormal growth of red blood cells, not a suppression of all blood cell types. B: Thrombocytopenia is the reduction in platelet count, not all blood cell types. D: Leukopenia is the decrease in only white blood cells, not all blood cell types. Therefore, C is the correct answer in this context.

Correct Answer: A

Rationale: The correct answer is A because both vitamin B12 and iron can have reduced absorption when taken with drugs that decrease stomach acid like PPIs and H2 blockers. This is due to the acidic environment in the stomach being necessary for the absorption of these nutrients. Therefore, taking them with these medications can lead to deficiencies. Methyldopa, metformin, and antibiotics do not directly interact with vitamin B12 or iron absorption, making them incorrect choices.

Correct Answer: A

Rationale: The correct answer is A: Coombs test. The Coombs test detects antibodies attached to red blood cells, a characteristic of hemolytic anemia. This test helps identify the presence of autoimmune hemolytic anemia. B: Genetic testing is not typically used to detect hemolytic anemia as it focuses on genetic mutations rather than the antibodies causing the condition. C: Peripheral blood smear can show abnormal red blood cell shapes in hemolytic anemia but does not directly detect the presence of antibodies causing the hemolysis. D: Schilling test is used to assess vitamin B12 absorption and is not relevant to detecting hemolytic anemia.