Which of the following is a consideration when administering salicylates?

Correct Answer: A

Rationale: The correct answer is A because administering salicylates with food, milk, antacids, or a large glass of water helps to minimize gastrointestinal side effects like stomach irritation and ulcers. Salicylates can be harsh on the stomach lining, so taking them with food or a buffer like milk or antacids can reduce irritation. Administering on an empty stomach (choice B) can increase the risk of stomach irritation. Crushing enteric-coated tablets (choice C) can lead to rapid absorption and increase the risk of side effects. Avoiding taking with water (choice D) is incorrect as water can help with swallowing and absorption.

Correct Answer: A

Rationale: Rationale: 1. Allopurinol inhibits xanthine oxidase enzyme, reducing uric acid levels. 2. Probenecid increases uric acid excretion, not inhibiting xanthine oxidase. 3. Colchicine is an anti-inflammatory agent for gout, not a xanthine oxidase inhibitor. 4. Leflunomide is a disease-modifying antirheumatic drug, not a xanthine oxidase inhibitor. In summary, Allopurinol (choice A) is the correct answer as it directly inhibits xanthine oxidase, while the other choices have different mechanisms of action not related to xanthine oxidase inhibition.

Correct Answer: D

Rationale: The correct answer is D because abruptly stopping prednisone can lead to adrenal insufficiency due to suppression of the body's natural cortisol production. This can result in potentially life-threatening symptoms. Choices A, B, and C are incorrect because while they are important considerations when taking prednisone, they are not as critical as ensuring the client understands the importance of tapering off the medication gradually to prevent adrenal insufficiency.

Correct Answer: B

Rationale: The correct answer is B: Iron deficiency anemia. Hookworm infection can lead to iron deficiency anemia by causing blood loss in the gastrointestinal tract. Hookworms feed on blood in the intestines, leading to chronic blood loss and subsequent iron deficiency. This type of anemia is characterized by low iron levels in the body, resulting in decreased production of hemoglobin and red blood cells. Hemolytic anemia (choice A) is caused by premature destruction of red blood cells, not blood loss. Megaloblastic anemia (choice C) is typically due to vitamin B12 or folate deficiency, not related to hookworm infestation. Aplastic anemia (choice D) is a condition where the bone marrow does not produce enough blood cells, not directly caused by hookworm infection.

Correct Answer: C

Rationale: The correct answer is C because myelodysplastic syndromes result from ineffective proliferation of cells of myeloid origin. This leads to abnormal development and functioning of blood cells. Choice A is incorrect as the disorders actually involve ineffective rather than increased proliferation. Choice B is incorrect as polycythemia vera is a separate disorder characterized by an overproduction of red blood cells. Choice D is incorrect as myelodysplastic syndromes specifically involve myeloid cells, not lymphoid cells.