Which of the following disorders results from a deficiency of factor VIII?

Correct Answer: C

Rationale: The correct answer is C: Hemophilia A. Factor VIII deficiency is characteristic of Hemophilia A. Factor VIII is crucial for blood clotting, and its deficiency leads to prolonged bleeding. Sickle cell disease (A) is a genetic disorder affecting red blood cells. Christmas disease (B) is another name for Hemophilia B, which results from a deficiency of factor IX, not factor VIII. Therefore, the incorrect choices are A, B, and D.

Correct Answer: B

Rationale: The correct answer is B. During a bone marrow biopsy, a needle is inserted into the bone to extract a sample. The client may experience a crunching sound or scraping sensation as the needle punctures the bone due to the nature of the procedure. This is because the bone is a hard structure, and the needle has to penetrate it to collect the sample. Choice A is incorrect because a bone marrow biopsy involves extracting a solid tissue sample, not fluid. Choice C is incorrect as additional people are not typically prohibited during the procedure, but proper sterile techniques are followed. Choice D is incorrect because sedation may or may not be given, and the client may still be aware of some sensations during the procedure.

Correct Answer: B

Rationale: The correct answer is B (4.6-6.0) because it represents the normal range for total Red Blood Cell (RBC) count in men, typically measured in millions per microliter. RBC count outside this range may indicate anemia or other health issues. Choice A (4.0-5.0) is too narrow and may miss slightly elevated RBC levels. Choice C (4.2-6.5) is too wide and includes values above the normal range. Choice D (4.0-6.0) is broader and includes lower values not typically seen in healthy men.

Correct Answer: C

Rationale: Step-by-step rationale: 1. Hydroxyurea inhibits ribonucleotide reductase, leading to decreased DNA synthesis. 2. This action is used in treating conditions like sickle cell anemia, where inhibiting DNA synthesis decreases RBC production. 3. Choice A is incorrect as hydroxyurea actually increases nitric oxide levels. 4. Choice B is incorrect as hydroxyurea decreases WBC production, including neutrophils and monocytes. 5. Choice D is incorrect as hydroxyurea does not increase RBC lifespan but instead decreases RBC production.

Correct Answer: B

Rationale: Step-by-step rationale: 1. Aplastic anemia is a rare disorder characterized by bone marrow failure. 2. While some drugs can cause bone marrow suppression, the mentioned drugs are not typically associated with aplastic anemia. 3. Lithium is linked to neutropenia, acetazolamide to aplastic anemia in rare cases, and aspirin to thrombocytopenia, not aplastic anemia. 4. Therefore, the correct answer is B: FALSE. Summary: - Choice A is incorrect because the drugs listed do not commonly induce aplastic anemia. - Choice C is incorrect as there is limited evidence supporting these drugs as common causes. - Choice D is incorrect as aplastic anemia induced by these drugs is not considered rare.