ATI LPN
Quiz Questions Hematologic System Questions
Question 1 of 5
Which of the following cells may develop in sites other than the bone marrow?
Correct Answer: B
Rationale: The correct answer is B: Lymphocyte. Lymphocytes can develop in sites other than the bone marrow, such as the thymus and lymph nodes. Monocytes, Megakaryocytes, and Neutrophils develop exclusively in the bone marrow. Monocytes differentiate into macrophages and dendritic cells, while Megakaryocytes produce platelets. Neutrophils are a type of white blood cell involved in the immune response. Therefore, only lymphocytes have the ability to develop outside the bone marrow, making choice B the correct answer.
Question 2 of 5
Which chromosomal abnormalities are associated with multiple myeloma? (Choose one)
Correct Answer: A
Rationale: The correct answer is A (t(11;14)) as this translocation is specifically associated with multiple myeloma, involving the cyclin D1 gene on chromosome 11. This translocation leads to overexpression of cyclin D1, promoting cell cycle progression and contributing to the pathogenesis of multiple myeloma. Choice B (t(9;22)) is associated with chronic myeloid leukemia, not multiple myeloma. Choice C (t(15;17)) is related to acute promyelocytic leukemia. Choice D (t(8;14)) is seen in Burkitt lymphoma, not multiple myeloma. Thus, the correct answer is A due to its direct association with multiple myeloma.
Question 3 of 5
A child stung by a bee experiences respiratory distress within minutes and lapses into unconsciousness. This reaction is probably mediated by
Correct Answer: A
Rationale: The correct answer is A: IgE antibody. IgE antibodies are involved in Type I hypersensitivity reactions, such as anaphylaxis caused by bee stings. IgE antibodies bind to mast cells and basophils, triggering the release of inflammatory mediators like histamine, causing respiratory distress and unconsciousness. IgG antibodies (choice B) are not typically involved in immediate hypersensitivity reactions. Sensitized T cells (choice C) are involved in delayed hypersensitivity reactions, not immediate ones like anaphylaxis. Complement (choice D) is part of the innate immune system and is not directly involved in IgE-mediated allergic reactions like anaphylaxis.
Question 4 of 5
Chemically-induced tumors have tumor-associated transplantation antigens that
Correct Answer: B
Rationale: The correct answer is B because tumor-associated transplantation antigens can vary between different tumors of different histologic types even if induced by the same carcinogen. This is due to the fact that different histologic types of tumors can express different antigens, leading to variations in the transplantation antigens. Choice A is incorrect because tumor-associated transplantation antigens can differ even with the same carcinogen. Choice C is incorrect because the strength of the antigens is not specified in the question. Choice D is incorrect as tumor-associated transplantation antigens can indeed induce an immune response.
Question 5 of 5
Natural killer cells are
Correct Answer: D
Rationale: The correct answer is D because natural killer cells are a type of innate immune cell that can recognize and kill virus-infected cells without the need for prior sensitization. They are part of the body's first line of defense against viral infections. Choice A is incorrect because B cells are a type of adaptive immune cell involved in antibody production, not natural killer cells. Choice B is incorrect because cytotoxic T cells are also adaptive immune cells that require prior sensitization to target specific antigens. Choice C is incorrect because immunization typically boosts adaptive immune responses involving B and T cells, not natural killer cells.