When the entire CBC is suppressed due to either anemia, infection, or hemorrhage is called?

Correct Answer: C

Rationale: The correct answer is C: Pancytopenia. Pancytopenia refers to a reduction in all three major blood cell types (red blood cells, white blood cells, and platelets). In the given scenario where the entire CBC is suppressed due to anemia, infection, or hemorrhage, it signifies a decrease in all blood cell types. A: Erythroplasia specifically refers to abnormal growth of red blood cells, not a suppression of all blood cell types. B: Thrombocytopenia is the reduction in platelet count, not all blood cell types. D: Leukopenia is the decrease in only white blood cells, not all blood cell types. Therefore, C is the correct answer in this context.

Correct Answer: A

Rationale: The correct answer is A: Coombs test. The Coombs test detects antibodies attached to red blood cells, a characteristic of hemolytic anemia. This test helps identify the presence of autoimmune hemolytic anemia. B: Genetic testing is not typically used to detect hemolytic anemia as it focuses on genetic mutations rather than the antibodies causing the condition. C: Peripheral blood smear can show abnormal red blood cell shapes in hemolytic anemia but does not directly detect the presence of antibodies causing the hemolysis. D: Schilling test is used to assess vitamin B12 absorption and is not relevant to detecting hemolytic anemia.

Correct Answer: A

Rationale: The correct answer is A: TRUE. Isozymes of 2C, specifically CYP2C9, play a crucial role in metabolizing warfarin. Variants of CYP2C9 can lead to variations in warfarin metabolism, affecting its efficacy and risk of bleeding. Therefore, isozymes of 2C can significantly impact warfarin therapy. Choice B (FALSE) is incorrect because multiple studies have shown the impact of CYP2C9 isozymes on warfarin metabolism. Choice C (Sometimes) is vague and does not acknowledge the consistent influence of CYP2C9 on warfarin. Choice D (Only in high doses) is incorrect as CYP2C9 variants affect warfarin metabolism irrespective of the dose administered.

Correct Answer: A

Rationale: The correct answer is A: Soccer-ball. In Chronic Lymphocytic Leukemia (CLL), lymphocytes typically appear small or slightly larger than normal, with hypercondensed nuclear chromatin and the presence of bare nuclei called 'smudge cells'. The comparison to a soccer-ball is apt as soccer-balls are relatively small, round, and have a unique pattern on their surface. Choices B, C, and D are incorrect as they do not accurately describe the characteristic appearance of lymphocytes in CLL. B: Basketball is too large and lacks the hypercondensed nuclear chromatin pattern. C: Football is not round and lacks the specific nuclear chromatin pattern. D: Tennis-ball is also too small and does not exhibit the characteristic appearance of CLL lymphocytes.

Correct Answer: D

Rationale: After adjusting for Kohler illumination, the light intensity should not be regulated through the condenser because it is meant to adjust the focus and light distribution, not intensity. The correct way to regulate light intensity is through the rheostat, not the condenser. Using a neutral density filter can help reduce light intensity, but it is not the primary method for regulation in Kohler illumination. Kohler magnifier is not used for light intensity regulation but for viewing the image.