What is the inheritance pattern of complete androgen insensitivity syndrome?

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Question 1 of 5

What is the inheritance pattern of complete androgen insensitivity syndrome?

Correct Answer: D

Rationale: Complete androgen insensitivity syndrome (CAIS) is caused by mutations in the AR gene on the X chromosome, following an X-linked recessive pattern (Choice D). Phenotypic females (46,XY) inherit a mutated X from carrier mothers, with males unaffected as they have one X. Autosomal dominant (Choice A) and recessive (Choice B) don’t apply to X-linked traits. Mitochondrial (Choice C) involves maternal transmission, unrelated here. X-linked recessive fits CAIS’s genetics.

Question 2 of 5

Phosphorus moves into the intracellular space resulting in hypophosphatemia in the following condition:

Correct Answer: C

Rationale: Respiratory alkalosis shifts phosphorus intracellularly due to alkalemia, lowering serum levels (UpToDate). Acidosis (A, D) shifts it out, and B, E have minimal effect.

Question 3 of 5

Gonadoblastoma may occur in the following condition:

Correct Answer: B

Rationale: Turner syndrome with Y-chromosome material raises gonadoblastoma risk due to dysgenetic gonads (NORD). Other conditions (A, C-E) lack this link.

Question 4 of 5

A child appears with metabolic acidosis. Basic laboratory tests should include all of the following except:

Correct Answer: D

Rationale: Liver enzymes aren’t routine for initial metabolic acidosis workup; A-C, E assess cause and severity (AAP).

Question 5 of 5

The most accurate assessment of gestational age at term is:

Correct Answer: C

Rationale: Abdominal circumference and femoral length together are most accurate at term (ACOG). A-D are less reliable late.

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