What is the average life span of normal human platelets in circulation?

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Question 1 of 5

What is the average life span of normal human platelets in circulation?

Correct Answer: C

Rationale: Normal human platelets have an average lifespan of 7-10 days in circulation (Choice C is 10 days), after which they are removed by the spleen and liver. 24 hours (Choice A) and 72 hours (Choice B) are too short, while 30 days (Choice D) exceeds physiological norms. 10 days is the widely accepted average.

Question 2 of 5

The physician noted pink to dark brown staining in diapers during a routine newborn physical examination. Most likely diagnosis is:

Correct Answer: C

Rationale: CEP causes porphyrin excretion, staining diapers pink to brown (NORD). PKU and homocystinuria affect amino acids, jaundice causes yellowing, and nephrotic syndrome involves protein loss.

Question 3 of 5

A girl with Turner syndrome developed some form of masculinization. Her mother is worried because her daughter might develop gonadoblastoma. The following screening test is indicated:

Correct Answer: D

Rationale: Screening for Y-chromosome material via karyotyping/FISH is key in Turner syndrome with masculinization to assess gonadoblastoma risk (Endocrine Society). A-D are nonspecific.

Question 4 of 5

Mode of inheritance in adrenoleukodystrophy is:

Correct Answer: B

Rationale: Adrenoleukodystrophy is X-linked , due to ABCD1 gene mutations (NORD). A, C-E don’t apply.

Question 5 of 5

Most nosocomial infections in neonatal intensive care unit (NICU) is associated with:

Correct Answer: A

Rationale: Intravascular catheters are the top source of NICU nosocomial infections due to bloodstream entry (CDC). B-E are less common.

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