What is the action of histamine-2 receptor antagonists (H2RAs) in the treatment of PUD?

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Chapter 15 The Gastrointestinal System Review Questions Questions

Question 1 of 5

What is the action of histamine-2 receptor antagonists (H2RAs) in the treatment of PUD?

Correct Answer: B

Rationale: The correct answer is B. H2RAs block acid secretion by inhibiting histamine. Histamine stimulates acid production by binding to H2 receptors on parietal cells. By blocking these receptors, H2RAs reduce acid secretion, providing relief in peptic ulcer disease (PUD). Choice A is incorrect because H2RAs do not neutralize gastric acid directly. Choice C is incorrect as H2RAs do not coat the stomach lining. Choice D is incorrect as H2RAs do not eradicate H. pylori, the bacteria commonly associated with PUD.

Question 2 of 5

A 35-year-old patient with a history of PUD presents with a sudden, sharp, and persistent pain in the upper abdomen that is worse with movement. What should the nurse suspect?

Correct Answer: C

Rationale: Sudden, sharp pain worsened by movement in a PUD patient suggests perforation, a medical emergency.

Question 3 of 5

A patient with a history of PUD is admitted for observation after a sudden onset of severe abdominal pain. What diagnostic test would the nurse anticipate being ordered first?

Correct Answer: B

Rationale: A CT scan is often first to quickly identify complications like perforation or bleeding in acute PUD presentations.

Question 4 of 5

A patient with PUD is prescribed a combination therapy of amoxicillin, clarithromycin, and a PPI. The nurse understands that this regimen is intended to:

Correct Answer: C

Rationale: This triple therapy eradicates H. pylori and reduces acid to heal ulcers.

Question 5 of 5

A patient with PUD presents with a sudden onset of severe abdominal pain, vomiting, and signs of peritonitis. What is the nurse's priority action?

Correct Answer: B

Rationale: Signs of peritonitis suggest perforation, requiring immediate physician notification.

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