What is a serious adverse effect of belimumab?

Correct Answer: A

Rationale: The correct answer is A: Acute pulmonary edema. Belimumab is a monoclonal antibody used to treat systemic lupus erythematosus, and one of its serious adverse effects is acute pulmonary edema. This can occur due to an allergic reaction to the medication, resulting in fluid accumulation in the lungs. Bone marrow suppression (choice B) is not a common adverse effect of belimumab. Retinal damage (choice C) is not associated with belimumab use. Hepatotoxicity (choice D) is a known adverse effect of some medications but is not a prominent concern with belimumab. Therefore, the correct answer is A, as it aligns with the drug's known adverse effects.

Correct Answer: C

Rationale: The correct answer is C: Ensure a patent airway while calling the Rapid Response Team. This is the most appropriate action because the client is showing signs of angioedema, a potentially life-threatening adverse reaction to angiotensin-converting enzyme (ACE) inhibitors. Angioedema can lead to airway obstruction and respiratory distress, so ensuring a patent airway is crucial. Calling the Rapid Response Team will provide immediate access to additional resources and expertise to manage the situation effectively. Choice A (Administer epinephrine) is incorrect because epinephrine is not the first-line treatment for angioedema caused by ACE inhibitors. Choice B (Apply oxygen) may be helpful but does not address the urgent need to secure the airway. Choice D (Reassure the client) is inappropriate as the situation requires immediate intervention to prevent respiratory compromise.

Correct Answer: D

Rationale: The correct answer is D, Mean corpuscular hemoglobin concentration (MCHC). MCHC represents the concentration of hemoglobin in a given volume of packed red blood cells. It is calculated by dividing the hemoglobin concentration by the hematocrit value. MCV (A) represents the average volume of red blood cells, not hemoglobin concentration. Red cell width (B) is not a standard measure of hemoglobin concentration. MCH (C) represents the average amount of hemoglobin in individual red blood cells, not the concentration in a given volume.

Correct Answer: A

Rationale: Neutrophils are not antigen presenting cells as they primarily function in innate immunity by phagocytosing pathogens. B cells, macrophages, and dendritic cells are antigen presenting cells that process and present antigens to activate adaptive immune responses. Neutrophils lack the specialized machinery for antigen presentation, making choice A the correct answer.

Correct Answer: B

Rationale: The correct answer is B: "Have you been camping in the last month?" This question is the first one to ask because the client presenting with a ring-like rash on the upper leg suggests a possible exposure to ticks, which are commonly found in outdoor environments like camping areas. Ticks can transmit Lyme disease, which often presents with a characteristic rash called erythema migrans. By asking about recent camping activities, the nurse can gather crucial information to assess the likelihood of a tick bite and the need for further evaluation or treatment. Choices A, C, and D are incorrect because they do not directly address the potential exposure to ticks from outdoor activities like camping. Asking about cats in the home (choice A) is more relevant for conditions like cat scratch fever. Inquiring about flu-like symptoms (choice C) and physical contact with others with a similar rash (choice D) may be important but are not as pertinent as determining outdoor activities that could lead to a tick bite.