Symptoms of withdrawal may include:

Correct Answer: D

Rationale: Choice D is correct because withdrawal can cause anxiety (CNS rebound), nausea (GI distress), and seizures (severe cases), depending on the drug, per clinical data. Choice A is incorrect alone as it's one symptom. Choice B is wrong by itself because nausea is just part. Choice C is incorrect solo since seizures are only one effect.

Correct Answer: A

Rationale: Choice A is correct because protein intake affects albumin levels, altering drug binding and free drug availability, directly impacting action. Choice B is incorrect as iron intake influences absorption of some drugs (e.g., tetracyclines), not action broadly. Choice C is wrong because vitamin D affects bone health, not drug action directly. Choice D is incorrect since only protein has a widespread pharmacokinetic impact.

Correct Answer: B

Rationale: Choice B is correct because St John's wort induces P-glycoprotein and CYP3A4, reducing digoxin levels and efficacy, a significant interaction. Choice A is incorrect as ginkgo biloba doesn't notably affect digoxin. Choice C is wrong because valerian root has minimal impact on digoxin pharmacokinetics. Choice D is incorrect since only St John's wort interacts markedly.

Correct Answer: B

Rationale: Choice B is correct because acetaminophen is safe for breastfeeding, with low milk levels and no significant infant effects, per AAP guidelines. Choice A is incorrect as fluoxetine's milk transfer risks infant exposure. Choice C is wrong because isotretinoin isn't safe—it's contraindicated in breastfeeding due to toxicity. Choice D is incorrect since only acetaminophen is safe.

Correct Answer: B

Rationale: Choice B is correct because tamper-proof paper helps prevent prescription fraud, a key precaution for controlled substances prone to abuse. Choice A is incorrect as faxing Schedule II prescriptions is restricted—originals are typically required. Choice C is wrong because pre-signed pads are insecure and discouraged. Choice D is incorrect since numbers alone don't enhance security and may confuse.

Correct Answer: A

Rationale: The correct answer is A because NPs need knowledge of herbal remedies to guide patients safely. Choice B is incorrect (prescribing lacks evidence base). Choice C is wrong (stopping not practical). Choice D is inaccurate (unregulated but not inherently unsafe).

Correct Answer: D

Rationale: Choice D is correct because enteric-coated tablets need ample fluid (e.g., 8 ounces) to ensure proper passage and dissolution in the intestines, not stomach, for optimal effect. Choice A is incorrect as avoiding other drugs isn't a general rule unless specified. Choice B is wrong because dissolving enteric-coated tablets destroys their protective coating. Choice C is incorrect since crushing negates the coating's purpose.

Correct Answer: A

Rationale: The correct answer is A because NPs need knowledge of herbal remedies to guide patients safely. Choice B is incorrect (prescribing lacks evidence base). Choice C is wrong (stopping not practical). Choice D is inaccurate (unregulated but not inherently unsafe).

Correct Answer: C

Rationale: Choice C is correct because choosing a drug covered by insurance ensures affordability and adherence, a practical consideration in rational drug selection. Choice A is incorrect as serious side effects typically deter use unless benefits outweigh risks, especially for non-life-threatening conditions. Choice B is wrong because dosing and location are secondary to efficacy and cost. Choice D is incorrect since insurance coverage is a valid factor.