ATI LPN
NCLEX PN Pharmacology Practice Questions Questions
Question 1 of 9
Nutritional deficiencies that may impact drug action include:
Correct Answer: A
Rationale: Choice A is correct because vitamin K deficiency reduces clotting factor synthesis, enhancing warfarin's anticoagulant effect, a direct drug action impact. Choice B is incorrect as vitamin C deficiency (scurvy) doesn't significantly alter drug action pharmacokinetically. Choice C is wrong because B12 deficiency affects neurology, not drug metabolism broadly. Choice D is incorrect since only vitamin K has a specific, notable drug interaction.
Question 2 of 9
Drugs that require a REMS program include:
Correct Answer: B
Rationale: Choice B is correct because isotretinoin requires a REMS due to teratogenicity, involving strict pregnancy prevention measures, unlike others. Choice A is incorrect as acetaminophen lacks serious enough risks for REMS. Choice C is wrong because ibuprofen's OTC status and safety profile don't warrant REMS. Choice D is incorrect since only isotretinoin applies.
Question 3 of 9
Risks to the breastfeeding infant include:
Correct Answer: A
Rationale: Choice A is correct because sedating drugs (e.g., opioids) in breast milk can cause infant drowsiness or respiratory depression, a primary risk. Choice B is incorrect as no drugs typically ‘stimulate growth' in this context—growth is natural. Choice C is wrong because acetaminophen is safe, with minimal risk. Choice D is incorrect since only A is a significant concern.
Question 4 of 9
Drugs that may cause gynecomastia in men include:
Correct Answer: A
Rationale: Choice A is correct because spironolactone blocks androgen receptors, causing gynecomastia, a well-documented side effect. Choice B is incorrect as atenolol (beta blocker) rarely causes it. Choice C is wrong because lisinopril (ACE inhibitor) doesn't typically lead to gynecomastia. Choice D is incorrect since only spironolactone is a clear culprit.
Question 5 of 9
Patients at higher risk for polypharmacy include:
Correct Answer: D
Rationale: Choice D is correct because the elderly (age-related diseases), those with chronic conditions (multiple meds), and patients with multiple providers (uncoordinated care) are prone to polypharmacy, per research. Choice A is incorrect alone as it's one group. Choice B is wrong by itself because chronic conditions are just part. Choice C is incorrect solo since multiple providers are only one factor.
Question 6 of 9
As patients age, it becomes particularly important to increase their intake of:
Correct Answer: D
Rationale: The correct answer is D because elderly are prone to B vitamin deficiencies due to poor intake. Choice A is incorrect (iron less critical). Choice B is wrong (omega-3 not primary). Choice C is inaccurate (vitamin C not highlighted).
Question 7 of 9
A patient is seen in the clinic with a 1-week history of frequent watery stools. The primary care NP learns that a family member had gastroenteritis a week prior. The patient was treated for a UTI with a sulfonamide antibiotic 2 months prior. The NP should suspect:
Correct Answer: A
Rationale: The correct answer is A because CDAD can occur up to 2 months post-antibiotic, causing diarrhea. Choice B is incorrect (viral possible but CDAD priority). Choice C is wrong (serum sickness not diarrhea-related). Choice D is inaccurate (UTI unrelated).
Question 8 of 9
The primary care NP is performing a physical examination on a 6-month-old infant with cerebral palsy who has not had previous immunizations. The NP plans to begin vaccinations and should include:
Correct Answer: A
Rationale: The correct answer is A because infants with stable neurologic conditions like cerebral palsy should receive DTaP. Choice B is incorrect (TdaP for adults). Choice C is wrong (TD incomplete). Choice D is inaccurate (tetanus alone insufficient).
Question 9 of 9
Patient education about drug storage should include:
Correct Answer: D
Rationale: Choice D is correct because educating on temperature (efficacy), child safety (prevents ingestion), and humidity avoidance (stability) ensures proper drug storage, per safety guidelines. Choice A is incorrect alone as it's one aspect. Choice B is wrong by itself because safety is just part. Choice C is incorrect solo since humidity is only one concern.