Miss Johnson is an asymptomatic 34 yo woman who presents for breast biopsy and EKG finds long QT interval >470 ms. Which describes the best treatment option?

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Question 1 of 5

Miss Johnson is an asymptomatic 34 yo woman who presents for breast biopsy and EKG finds long QT interval >470 ms. Which describes the best treatment option?

Correct Answer: A

Rationale: For asymptomatic long QT syndrome with QT >470 ms, beta blockers are the first-line treatment to reduce risk of arrhythmias, with monitoring for symptoms.

Question 2 of 5

Which of the following does not increase the risk of developing endometrial carcinoma?

Correct Answer: D

Rationale: Obesity, unopposed estrogen (e.g., from hormone replacement therapy without progesterone), and anovulation increase endometrial carcinoma risk by elevating estrogen levels. Veganism does not inherently affect estrogen levels or endometrial cancer risk, making it the correct answer.

Question 3 of 5

A colleague's wife presents to your office, ill appearing, w/ severe abdominal pain and bloody diarrhea. Dietary hx is not helpful. What should NOT be offered?

Correct Answer: C

Rationale: Empiric quinolones should not be offered without confirming the diagnosis as inappropriate antibiotic use can worsen outcomes like in Clostridioides difficile infections.

Question 4 of 5

26-year-old man is found to have IgA nephropathy on a renal biopsy performed for intermittent hematuria and persistent proteinuria(UPC 1.8). His serum creatinine is 1.2 mg/dl. UPC declines to 1.5 and the serum creatinine increases to 1.3 mg/dl after 3 months of lisinopril 10 mg/d. The urinary Na excretion is 180 mmol/d. Which ONE of the following should be done next?

Correct Answer: D

Rationale: High sodium intake can reduce the effectiveness of ACE inhibitors like lisinopril. A low-sodium diet will enhance the drug's efficacy thus reducing proteinuria and protecting renal function.

Question 5 of 5

75-y male presents with a fifteen-pound weight loss over the last 3 months. He denies fever, chills, or night sweats. Travel history is negative. Prior occupation significant for many years of mining. Medical history otherwise unremarkable. VS stable. Physical exam is normal with the exception of decreased breath sounds bilaterally. CT chest one year ago showed upper lobe scarring and nodularity along with eggshell calcifications in the hilar region. Tuberculin skin testing performed 6 months ago was negative. What is the most appropriate next step?

Correct Answer: C

Rationale: Weight loss and mining history (silicosis risk) with prior CT findings (eggshell calcifications) raise concern for progressive disease, possibly malignancy. A repeat CT chest is the best next step to assess interval change, per occupational lung disease workup.

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