In patients with low numbers of neoplastic cells, sometimes due to treatment, PCR to amplify DNA can improve sensitivity, and detect signs of relapse.

Correct Answer: A

Rationale: The correct answer is A: TRUE. PCR amplifies DNA, making it sensitive enough to detect low numbers of neoplastic cells, even in patients with reduced cell counts due to treatment. This can help in early detection of relapse. Choice B is incorrect because PCR can indeed improve sensitivity in such cases. Choice C is incorrect as PCR consistently enhances sensitivity. Choice D is incorrect as PCR can be used in both remission and relapse scenarios.

Correct Answer: A

Rationale: The correct answer is A (2). RPI (Reticulocyte Production Index) is calculated as: Observed Reticulocyte Count (%) x (Patient's Hct/Normal Hct). Given values: Observed reticulocyte count=6%, Hct=30%. Therefore, RPI = 6% x (30%/45%) = 6% x 0.67 = 4.02 ≈ 4. Since RPI is rounded to the nearest whole number, the correct RPI would be 4. Therefore, the correct answer is A (2). Other choices (B, C, D) are incorrect as they do not result from the correct calculation of RPI.

Correct Answer: C

Rationale: The correct answer is C: Condenser. The condenser gathers, organizes, and directs light through the specimen to improve contrast and resolution. It focuses the light onto the specimen, making it more visible. The other choices are incorrect because the ocular (A) is the eyepiece, the objective lens (B) magnifies the specimen, and the optical tube (D) holds the ocular and objective together.

Correct Answer: B

Rationale: The correct answer is B: Easy bruising. Immune thrombocytopenia purpura is characterized by low platelet count, leading to easy bruising. Fever (A) and joint pain (C) are not typical symptoms of ITP. Hair loss (D) is not associated with this condition. Easy bruising is a key sign due to decreased platelets preventing proper blood clotting.

Correct Answer: B

Rationale: The correct answer is B: RBC protection against oxidative damage. Glucose-6-phosphate dehydrogenase (G6PD) enzyme plays a crucial role in protecting red blood cells (RBCs) from oxidative damage by generating NADPH, which helps in neutralizing reactive oxygen species. G6PD deficiency leads to RBCs being more susceptible to oxidative stress, causing hemolysis. Choice A (Clotting factor production) is incorrect because G6PD is not directly involved in clotting factor production. Choice C (Platelet activation) is incorrect as G6PD deficiency does not affect platelet activation. Choice D (White cell proliferation) is incorrect as G6PD deficiency primarily affects RBCs, not white cell proliferation.