ATI LPN
LPN Pharmacology Questions Questions
Question 1 of 9
In every state, prescriptive authority for NPs includes the ability to write prescriptions:
Correct Answer: B
Rationale: The correct answer is B because all states grant NPs some prescriptive authority, but it’s often limited to specific drug classes. Choice A is incorrect as not all states allow controlled substances. Choice C is wrong since physician involvement is required in many states. Choice D is inaccurate as full independence isn’t universal.
Question 2 of 9
Drugs that are affected by genetic polymorphisms of TPMT include:
Correct Answer: B
Rationale: Choice B is correct because azathioprine's metabolism via TPMT (thiopurine methyltransferase) varies genetically, risking toxicity in poor metabolizers if not adjusted. Choice A is incorrect as warfarin uses CYP2C9 and VKORC1, not TPMT. Choice C is wrong because acetaminophen isn't metabolized by TPMT—it's glucuronidated. Choice D is incorrect since only azathioprine is TPMT-dependent.
Question 3 of 9
An adolescent girl reports having heavy menstrual periods. Her hemoglobin is consistently on the low end of the normal range. The primary care NP should prescribe:
Correct Answer: C
Rationale: The correct answer is C because oral contraceptives reduce menstrual blood loss, preventing iron-deficiency anemia. Choice A is incorrect (iron for active anemia). Choice B is wrong (folic acid not preventive here). Choice D is inaccurate (diet insufficient).
Question 4 of 9
The time required for the amount of drug in the body to decrease by 50% is called:
Correct Answer: B
Rationale: Choice B is correct because half-life is the time for a drug's concentration to decrease by 50%, a key pharmacokinetic parameter for dosing. Choice A is incorrect as steady state is when levels stabilize, not halve. Choice C is wrong because phase II metabolism is a process, not a time measure. Choice D is incorrect since ‘reduced bioavailability time' isn't a recognized term.
Question 5 of 9
Patient education regarding prescribed medication includes:
Correct Answer: B
Rationale: Choice B is correct because educating patients about expected adverse reactions prepares them to manage side effects and seek help if needed, enhancing safety and adherence. Choice A is incorrect as reading level should match the patient's, not a fixed standard. Choice C is wrong because storing leftovers encourages misuse—antibiotics should be completed. Choice D is incorrect since language should suit the patient, not always English.
Question 6 of 9
An NP learns that a 90-year-old patient is chronically constipated and has frequent problems with acid reflux. The NP notes a weight loss of 20 pounds in the previous 6 months. Which of the following drugs that this patient is taking is cause for concern?
Correct Answer: B
Rationale: The correct answer is B because naproxen, highly protein-bound, can become toxic with low albumin from malnutrition, as seen in this patient’s weight loss. Choice A is incorrect as quinidine isn’t primarily protein-bound related. Choice C is wrong since calcium citrate isn’t affected this way. Choice D is inaccurate as calcium channel blockers have different concerns.
Question 7 of 9
A nurse is assessing a client who is taking hydrocodone. Which of the following findings should the nurse report to the provider?
Correct Answer: D
Rationale: The correct answer is D: Respiratory depression. Hydrocodone is an opioid medication that can cause respiratory depression, a serious side effect that should be reported immediately to the healthcare provider. Constipation, sedation, and dry mouth are common side effects of hydrocodone but are not as concerning as respiratory depression. Constipation can be managed with lifestyle modifications and medications, sedation may improve with time or dosage adjustments, and dry mouth is a common and usually benign side effect.
Question 8 of 9
A woman who takes an angiotensin converting enzyme inhibitor for hypertension tells her primary care NP that she is trying to get pregnant. The NP should:
Correct Answer: A
Rationale: The correct answer is A because ACE inhibitors are contraindicated in pregnancy and should be replaced with safer options like methyldopa. Choice B is incorrect (lowering dose still risky). Choice C is wrong (increasing not indicated). Choice D is inaccurate (ARBs also contraindicated).
Question 9 of 9
Drugs that may require lower doses in the elderly include:
Correct Answer: C
Rationale: Choice C is correct because amoxicillin requires lower doses in the elderly due to decreased renal function, reducing clearance and risking toxicity. Choice A is incorrect as acetaminophen doses are standard unless liver issues exist. Choice B is wrong because amitriptyline is avoided, not just lowered. Choice D is incorrect since only amoxicillin typically needs adjustment.