Drugs that are commonly used off-label include:

Correct Answer: D

Rationale: Choice D is correct because gabapentin (e.g., anxiety), amitriptyline (e.g., pain), and quetiapine (e.g., insomnia) are often used off-label, supported by evidence, per clinical practice. Choice A is incorrect alone as it's one drug. Choice B is wrong by itself because amitriptyline is just part. Choice C is incorrect solo since quetiapine is only one agent.

Correct Answer: D

Rationale: Choice D is correct because education (awareness), access limits (e.g., PDMPs), and screening (early intervention) all prevent abuse, per public health strategies. Choice A is incorrect alone as it's one method. Choice B is wrong by itself because access is just part. Choice C is incorrect solo since screening is only one approach.

Correct Answer: D

Rationale: Choice D is correct because increasing doses (short-term fix), switching drugs (new mechanism), and drug holidays (reset sensitivity) all manage tolerance, per clinical strategies. Choice A is incorrect alone as it's one method. Choice B is wrong by itself because switching is just part. Choice C is incorrect solo since holidays are only one option.

Correct Answer: B

Rationale: The correct answer is B because all states grant NPs some prescriptive authority, but it’s often limited to specific drug classes. Choice A is incorrect as not all states allow controlled substances. Choice C is wrong since physician involvement is required in many states. Choice D is inaccurate as full independence isn’t universal.

Correct Answer: B

Rationale: The correct answer is B because protein-bound drugs compete for albumin, requiring monitoring to adjust dosing. Choice A is incorrect as increasing doses without monitoring is risky. Choice C is wrong since dietary protein doesn’t affect this. Choice D is inaccurate as staggering doesn’t resolve binding issues.