ATI LPN
Pharmacology NCLEX PN Questions Questions
Question 1 of 9
Drugs listed on the Beers Criteria include:
Correct Answer: B
Rationale: Choice B is correct because diphenhydramine is on the Beers Criteria due to anticholinergic risks like confusion and falls in the elderly. Choice A is incorrect as acetaminophen is safe. Choice C is wrong because amoxicillin isn't listed. Choice D is incorrect since only diphenhydramine fits.
Question 2 of 9
Factors that affect gastric drug absorption include:
Correct Answer: C
Rationale: Choice C is correct because lipid solubility affects gastric drug absorption by determining how easily a drug crosses the stomach's lipid membranes, a key pharmacokinetic factor. Choice A is incorrect as liver enzyme activity impacts metabolism, not gastric absorption. Choice B is wrong because protein binding affects distribution, not initial absorption. Choice D is incorrect since chewing and swallowing influence administration, not the absorption process in the stomach.
Question 3 of 9
Nutritional supplements that may serve as alternatives to prescription medications include:
Correct Answer: D
Rationale: Choice D is correct because calcium carbonate binds phosphate (e.g., in renal disease), melatonin aids sleep (alternative to sedatives), and omega-3s lower triglycerides (like fibrates)—all serve as alternatives. Choice A is incorrect alone as it's one example. Choice B is wrong by itself because it misses other options. Choice C is incorrect solo since it excludes additional alternatives.
Question 4 of 9
A primary care NP will begin practicing in a state in which the governor has opted out of the federal facility reimbursement requirement. The NP should be aware that this defines how NPs may write prescriptions:
Correct Answer: B
Rationale: The correct answer is B because the 2001 CMS rule change allows CRNAs to prescribe without supervision in states opting out, specifically in hospital settings. Choice A is incorrect as it applies to private practice, not CRNAs. Choice C is wrong since it misinterprets reimbursement implications. Choice D is inaccurate as supervision isn’t required in opted-out states for CRNAs.
Question 5 of 9
Factors that affect gastric drug absorption include:
Correct Answer: C
Rationale: Choice C is correct because lipid solubility affects gastric drug absorption by determining how easily a drug crosses the stomach's lipid membranes, a key pharmacokinetic factor. Choice A is incorrect as liver enzyme activity impacts metabolism, not gastric absorption. Choice B is wrong because protein binding affects distribution, not initial absorption. Choice D is incorrect since chewing and swallowing influence administration, not the absorption process in the stomach.
Question 6 of 9
A primary care NP wishes to order a drug that will be effective immediately after administration of the drug. Which route should the NP choose?
Correct Answer: C
Rationale: The correct answer is C because sublingual administration allows rapid absorption into the bloodstream, bypassing liver metabolism for immediate effect. Choice A is incorrect due to unpredictable rectal absorption. Choice B is wrong as topical is slowest. Choice D is inaccurate as intramuscular is slower than sublingual.
Question 7 of 9
The parent of a 2-month-old infant who will soon begin daycare refuses the rotavirus vaccine (RV) because of fears of intussusception. The parent tells the primary care NP that the daycare is strict about preventing infants who have fever or gastrointestinal symptoms from attending. The NP should tell the parent that:
Correct Answer: B
Rationale: The correct answer is B because asymptomatic rotavirus spread is possible, bypassing daycare rules. Choice A is incorrect (herd immunity unreliable here). Choice C is wrong (intussusception risk reduced, not absent). Choice D is inaccurate (antibiotics ineffective).
Question 8 of 9
Drugs that may cause contraceptive failure include:
Correct Answer: B
Rationale: Choice B is correct because carbamazepine induces CYP3A4, speeding contraceptive metabolism and risking failure, per pharmacology data. Choice A is incorrect as warfarin doesn't affect contraceptive efficacy. Choice C is wrong because acetaminophen has no such interaction. Choice D is incorrect since only carbamazepine applies.
Question 9 of 9
Two different pain medications are given together for pain relief. The drug-drug interaction is:
Correct Answer: D
Rationale: Choice D is correct because giving two pain medications together typically results in an additive effect, where their combined relief equals the sum of their individual effects, a common strategy in pain management. Choice A is incorrect as synergy implies a greater-than-sum effect, not specified here. Choice B is wrong because antagonism reduces effects, opposite to the goal. Choice C is incorrect since potentiation enhances one drug's effect by another, not necessarily equal summing.