An NP is prescribing an antibiotic for a child who will need to take a total of 750 mg per day. Which dosing regimen should the NP prescribe to promote compliance?

Correct Answer: C

Rationale: The correct answer is C because a higher concentration (500 mg/5 mL) and bid dosing simplifies administration, enhancing compliance. Choice A is incorrect (lower concentration, less convenient). Choice B is wrong (tid less convenient). Choice D is inaccurate (tid and lower dose inconvenient).

Correct Answer: A

Rationale: Choice A is correct because some patients perceive brand-name drugs as higher quality due to marketing or familiarity, despite bioequivalence. Choice B is incorrect as generics are cheaper, not brand-name. Choice C is wrong because side effects are equivalent. Choice D is incorrect since only A applies.

Correct Answer: A

Rationale: The correct answer is A because nonlinear kinetics means unpredictable elimination, requiring close monitoring due to a narrow therapeutic window. Choice B is incorrect as a high loading dose risks toxicity. Choice C is wrong since creatinine monitoring isn’t specific to nonlinear kinetics. Choice D is inaccurate as route doesn’t address kinetics.

Correct Answer: A

Rationale: Choice A is correct because some patients perceive brand-name drugs as higher quality due to marketing or familiarity, despite bioequivalence. Choice B is incorrect as generics are cheaper, not brand-name. Choice C is wrong because side effects are equivalent. Choice D is incorrect since only A applies.

Correct Answer: A

Rationale: Choice A is correct because protein intake affects albumin levels, altering drug binding and free drug availability, directly impacting action. Choice B is incorrect as iron intake influences absorption of some drugs (e.g., tetracyclines), not action broadly. Choice C is wrong because vitamin D affects bone health, not drug action directly. Choice D is incorrect since only protein has a widespread pharmacokinetic impact.

Correct Answer: C

Rationale: Choice C is correct because choosing a drug covered by insurance ensures affordability and adherence, a practical consideration in rational drug selection. Choice A is incorrect as serious side effects typically deter use unless benefits outweigh risks, especially for non-life-threatening conditions. Choice B is wrong because dosing and location are secondary to efficacy and cost. Choice D is incorrect since insurance coverage is a valid factor.

Correct Answer: A

Rationale: The correct answer is A because nonlinear kinetics means unpredictable elimination, requiring close monitoring due to a narrow therapeutic window. Choice B is incorrect as a high loading dose risks toxicity. Choice C is wrong since creatinine monitoring isn’t specific to nonlinear kinetics. Choice D is inaccurate as route doesn’t address kinetics.

Correct Answer: D

Rationale: Choice D is correct because acetaminophen (high doses), NSAIDs (e.g., ibuprofen), and aminoglycosides (e.g., gentamicin) can impair renal function, worsened by age-related decline, per nephrology data. Choice A is incorrect alone as it's one risk. Choice B is wrong by itself because NSAIDs are just part. Choice C is incorrect solo since aminoglycosides are only one class.

Correct Answer: D

Rationale: Choice D is correct because poor handwriting, sound-alike names (e.g., Celebrex vs. Celexa), and look-alike packaging all contribute to medication errors, per safety studies. Choice A is incorrect alone as it's one cause. Choice B is wrong by itself because sound-alikes are just one risk. Choice C is incorrect solo since packaging is only part of the problem.