An infant is born following premature delivery. Multiple external congenital anomalies are noted. The infant exhibits a seizure soon after birth. The blood glucose is 19 mg/dL. Which of the following maternal diseases is the most likely cause for the observed findings in this infant?

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Question 1 of 5

An infant is born following premature delivery. Multiple external congenital anomalies are noted. The infant exhibits a seizure soon after birth. The blood glucose is 19 mg/dL. Which of the following maternal diseases is the most likely cause for the observed findings in this infant?

Correct Answer: B

Rationale: The findings are complications of diabetes with pregnancy, and the malformations suggest that hyperglycemia preceded the pregnancy, and type 2 diabetes is quite common, even now in women of childbearing age. The neonatal hypoglycemia is a consequence of excessive islet beta-cell function from having been in a hyperglycemic environment.

Question 2 of 5

Diabetes mellitus is a deficiency or limited activity of which hormone?

Correct Answer: D

Rationale: Diabetes mellitus results from insulin deficiency (T1DM) or resistance (T2DM), impairing glucose uptake.

Question 3 of 5

Which of the following is responsible for closing the left AV valve?

Correct Answer: C

Rationale: Ventricular systole closes mitral valve as ventricular pressure exceeds atrial.

Question 4 of 5

An obstruction in blood flow to the kidneys would most likely result in:

Correct Answer: C

Rationale: Renal hypoxia from obstruction triggers EPO release to boost RBC production.

Question 5 of 5

Any of the following may provoke an immune response except:

Correct Answer: D

Rationale: All can trigger immunity: injury, pathogens, cancer, and autoimmunity.

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