A transmitter substance released from a presynaptic neuron activates a second messenger G-protein system in the postsynaptic neuron. Which one of the following postsynaptic responses to the transmitter substance is NOT a possible outcome?

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Question 1 of 5

A transmitter substance released from a presynaptic neuron activates a second messenger G-protein system in the postsynaptic neuron. Which one of the following postsynaptic responses to the transmitter substance is NOT a possible outcome?

Correct Answer: D

Rationale: G-protein activation can open ion channels, activate cAMP/cGMP, or trigger gene transcription, but not directly close ion channels. TMP13 pp. 583-584

Question 2 of 5

Which of the following is the basis for referred pain?

Correct Answer: D

Rationale: Convergence of visceral and somatic pain signals onto dorsal horn neurons causes referred pain. TMP13 p. 626

Question 3 of 5

An input neuron to a diverging circuit causes the membrane potential of a target neuron to change from -65 millivolts to -55 millivolts. Which of the following best describes this change in membrane potential (in millivolts)?

Correct Answer: A

Rationale: A depolarizing shift from -65 to -55 mV is an excitatory postsynaptic potential of +10 mV. TMP13 p. 588

Question 4 of 5

A 53-year-old woman with celiac disease visits the physician because of difficulty seeing at night. The woman has frequent, foul-smelling stools. Stool analysis reveals a high content of partially digested fat. A decrease in blood levels of which of the following is the most likely cause of her night blindness?

Correct Answer: D

Rationale: Vitamin A malabsorption in celiac disease reduces rhodopsin synthesis, causing night blindness. TMP13 pp. 648-649

Question 5 of 5

A 40-year-old woman is admitted emergently to the hospital because of sudden, severe pain in her right eye. Tests show an intraocular pressure of 30 mm Hg in her right eye; the intraocular pressure of her left eye is 15 mm Hg. Which of the following is the most likely cause of eye pain in this woman?

Correct Answer: A

Rationale: Acute angle-closure glaucoma causes sudden, severe pain with high intraocular pressure due to angle closure. TMP13 p. 646

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