ATI LPN
NCLEX PN Pharmacology Questions Questions
Question 1 of 9
A patient who has HIV is being treated with Emtriva. The patient develops hepatitis B. The primary care NP should contact the patient's infectious disease specialist to discuss:
Correct Answer: B
Rationale: The correct answer is B because Truvada (Emtriva + tenofovir) treats both HIV and hepatitis B effectively. Choice A is incorrect (zidovudine not for hepatitis B). Choice C is wrong (tenofovir alone insufficient). Choice D is inaccurate (Combivir unnecessary).
Question 2 of 9
A parent whose child received a fourth DTaP at a recent 15-month visit calls the primary care NP to report that the child is fussy, has a temperature of 38.3°C, and has redness and swelling at the injection site. The NP should:
Correct Answer: D
Rationale: The correct answer is D because these are common, mild reactions managed symptomatically. Choice A is incorrect (hospitalization not needed). Choice B is wrong (mild reaction isn’t a contraindication). Choice C is inaccurate (not severe enough for VAERS).
Question 3 of 9
As primary care nurse practitioners (NPs) continue to develop their role as prescribers of medications, it will be important to:
Correct Answer: B
Rationale: The correct answer is B because NPs should build expertise from physicians’ past experiences and evidence-based practice to enhance prescribing roles. Choice A is impractical as matching physician expertise isn’t the goal. Choice C is incorrect since NPs aim for independent practice, not supervision. Choice D is wrong as pharmaceutical reps provide biased info, unlike unbiased academic sources.
Question 4 of 9
Drug factors that affect breast milk excretion include:
Correct Answer: D
Rationale: Choice D is correct because maternal dose (higher means more in milk), lipid solubility (increases milk passage), and half-life (longer increases exposure) all affect drug excretion into breast milk, per pharmacokinetic principles. Choice A is incorrect alone as it's one factor. Choice B is wrong by itself because solubility is just part. Choice C is incorrect solo since half-life is only one aspect.
Question 5 of 9
Drugs that are contraindicated in children include:
Correct Answer: B
Rationale: Choice B is correct because tetracycline is contraindicated in children under 8 due to permanent tooth staining and bone effects, per FDA warnings. Choice A is incorrect as acetaminophen is safe and standard. Choice C is wrong because amoxicillin is widely used in kids. Choice D is incorrect since only tetracycline is contraindicated.
Question 6 of 9
Drugs rated AB in the Orange Book are:
Correct Answer: A
Rationale: Choice A is correct because an AB rating in the Orange Book means the generic is bioequivalent—same efficacy and safety—as the brand-name drug, per FDA standards. Choice B is incorrect as cost isn't part of the rating. Choice C is wrong because color isn't evaluated. Choice D is incorrect since only A applies.
Question 7 of 9
Steady state is:
Correct Answer: B
Rationale: Choice B is correct because steady state occurs when drug input (absorption) equals output (excretion), maintaining constant levels over time. Choice A is incorrect as absorption exceeding excretion describes initial dosing, not steady state. Choice C is wrong because steady state can be therapeutic or toxic, not just below toxicity. Choice D is incorrect since only B defines steady state accurately.
Question 8 of 9
Information sources that may be used to determine drug-herb interactions include:
Correct Answer: D
Rationale: Choice D is correct because pharmacists provide clinical expertise, Medline offers peer-reviewed studies, and the Natural Medicines Database specializes in herb-drug interactions—all are valid sources. Choice A is incorrect alone as it limits to one resource. Choice B is wrong by itself because it misses practical and specialized inputs. Choice C is incorrect solo since it excludes other valuable sources.
Question 9 of 9
Information sources that may be used to determine drug-herb interactions include:
Correct Answer: D
Rationale: Choice D is correct because pharmacists provide clinical expertise, Medline offers peer-reviewed studies, and the Natural Medicines Database specializes in herb-drug interactions—all are valid sources. Choice A is incorrect alone as it limits to one resource. Choice B is wrong by itself because it misses practical and specialized inputs. Choice C is incorrect solo since it excludes other valuable sources.