A nurse is transfusing a unit of B-positive fresh frozen plasma to a client whose blood type is O-negative. Which of the following actions should the nurse take?

Correct Answer: A

Rationale: The correct answer is A because transfusing blood products of an incompatible blood type can lead to severe reactions, including hemolysis. In this case, giving B-positive plasma to an O-negative recipient can cause a transfusion reaction due to ABO incompatibility. The nurse should stop the transfusion immediately to prevent harm to the client. Starting an IV infusion of normal saline helps maintain the client's fluid volume and supports kidney function in case of hemolysis. Choices B, C, and D are incorrect because continuing the transfusion, monitoring for fever, or administering antihistamines do not address the immediate risk of ABO incompatibility and potential severe transfusion reactions in this situation.

Correct Answer: A

Rationale: Step-by-step rationale: 1. Celecoxib is a selective COX-2 inhibitor used for pain and inflammation. 2. Studies have shown celecoxib increases the risk of cardiac events. 3. This is due to its mechanism of action affecting prostaglandins. 4. Prostaglandins play a role in cardiovascular homeostasis. Summary: - Choice A is correct as cardiac risks are a specific consideration for celecoxib. - Choices B, C, and D are incorrect as celecoxib is not primarily associated with increased risk of GI bleeding, renal failure, or CNS effects.

Correct Answer: A

Rationale: The correct answer is A, Belimumab. Belimumab is a monoclonal antibody that targets B-lymphocyte stimulator protein, specifically approved for systemic lupus erythematosus (SLE). It helps reduce autoantibody production and inflammation in SLE patients. Methotrexate (B), Hydroxychloroquine (C), and Leflunomide (D) are not monoclonal antibodies. Methotrexate is a DMARD, Hydroxychloroquine is an antimalarial, and Leflunomide is a DMARD used for rheumatoid arthritis, not specifically for SLE.

Correct Answer: A

Rationale: The correct answer is A: Colchicine. Colchicine is used to treat acute gout attacks by reducing inflammation and pain caused by uric acid crystals in the joints. It works by inhibiting the inflammatory response to these crystals. Allopurinol, Febuxostat, and Probenecid are used for long-term management of gout by lowering uric acid levels, not for acute attacks. Colchicine is specifically indicated for treating acute gout attacks due to its anti-inflammatory properties.

Correct Answer: C

Rationale: Rationale: Choice C is the correct answer because it states an incorrect fact about Lyme disease. Lyme disease, if left untreated, is not usually fatal. It can lead to serious complications but is rarely fatal. This indicates a need for review. Choices A, B, and D are incorrect as they provide accurate information about Lyme disease prevention, symptoms, and treatment duration, respectively.