A newborn boy appears with ambiguous genitalia, palpable gonads in labioscrotal folds, and a 46,XY karyotype. Most likely diagnosis is:

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Question 1 of 5

A newborn boy appears with ambiguous genitalia, palpable gonads in labioscrotal folds, and a 46,XY karyotype. Most likely diagnosis is:

Correct Answer: B

Rationale: Androgen insensitivity syndrome fits XY karyotype and palpable gonads, per AAP (doc p148, Q560).

Question 2 of 5

Best diagnostic test for Cushing syndrome is:

Correct Answer: C

Rationale: 24-hour urinary free cortisol screens for Cushing syndrome, per AAP (doc p150, Q592).

Question 3 of 5

A 3-month-old infant presents with poor feeding and tachypnea. Chest x-ray shows cardiomegaly. Most likely diagnosis is:

Correct Answer: B

Rationale: CHF features poor feeding, tachypnea, and cardiomegaly, per AHA. A, C-E differ.

Question 4 of 5

A 2-year-old boy presents with a limp and hip pain. X-ray shows a lytic lesion. Most likely diagnosis is:

Correct Answer: B

Rationale: Ewing sarcoma presents with lytic lesions, per NCI. A, C-E differ.

Question 5 of 5

A 3-year-old boy presents with fever and a limp. Hip aspiration shows pus. Most likely diagnosis is:

Correct Answer: B

Rationale: Septic arthritis fits fever and pus, per AAP. A, C-E lack pus.

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