A child suspected of having sickle cell disease is seen in a clinic, and laboratory studies are performed. A nurse checks the lab results, knowing that which of the following would be increased in this disease?

Correct Answer: C

Rationale: The correct answer is C: Reticulocyte count. In sickle cell disease, there is a chronic hemolytic anemia leading to increased destruction of red blood cells. As a compensatory mechanism, the bone marrow increases production of immature red blood cells called reticulocytes. This results in an elevated reticulocyte count in sickle cell disease. Platelet count (A) is typically not affected in sickle cell disease. Hematocrit level (B) may be decreased due to anemia. Hemoglobin level (D) may also be decreased due to the chronic hemolysis.

Correct Answer: B

Rationale: Correct Answer: B - Avoid exposure to others with acute infection Rationale: 1. Patients with aplastic anemia have compromised immune systems. 2. Acute infections can be life-threatening for these patients. 3. Teaching the patient to avoid exposure to infections is crucial for preventing complications. 4. This concept directly relates to health maintenance by reducing the risk of infections. Summary: - Choice A: Nutrition is important but not the most critical for aplastic anemia patients. - Choice C: While stress management is beneficial, infection prevention is more vital for health maintenance. - Choice D: Sleep is essential, but avoiding infections takes precedence for aplastic anemia patients.

Correct Answer: B

Rationale: The correct answer is B. During a bone marrow biopsy, a needle is inserted into the bone to extract a sample. The client may experience a crunching sound or scraping sensation as the needle punctures the bone due to the nature of the procedure. This is because the bone is a hard structure, and the needle has to penetrate it to collect the sample. Choice A is incorrect because a bone marrow biopsy involves extracting a solid tissue sample, not fluid. Choice C is incorrect as additional people are not typically prohibited during the procedure, but proper sterile techniques are followed. Choice D is incorrect because sedation may or may not be given, and the client may still be aware of some sensations during the procedure.

Correct Answer: B

Rationale: The correct answer is B (4.6-6.0) because it represents the normal range for total Red Blood Cell (RBC) count in men, typically measured in millions per microliter. RBC count outside this range may indicate anemia or other health issues. Choice A (4.0-5.0) is too narrow and may miss slightly elevated RBC levels. Choice C (4.2-6.5) is too wide and includes values above the normal range. Choice D (4.0-6.0) is broader and includes lower values not typically seen in healthy men.

Correct Answer: C

Rationale: Step-by-step rationale: 1. Hydroxyurea inhibits ribonucleotide reductase, leading to decreased DNA synthesis. 2. This action is used in treating conditions like sickle cell anemia, where inhibiting DNA synthesis decreases RBC production. 3. Choice A is incorrect as hydroxyurea actually increases nitric oxide levels. 4. Choice B is incorrect as hydroxyurea decreases WBC production, including neutrophils and monocytes. 5. Choice D is incorrect as hydroxyurea does not increase RBC lifespan but instead decreases RBC production.