A 5-year-old boy presents with difficulty walking and muscle weakness. Creatine kinase is 10,000 U/L. Most likely diagnosis is:

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Question 1 of 5

A 5-year-old boy presents with difficulty walking and muscle weakness. Creatine kinase is 10,000 U/L. Most likely diagnosis is:

Correct Answer: B

Rationale: Duchenne muscular dystrophy features weakness and high CK in boys, per MDA. A, C-E have lower CK.

Question 2 of 5

A 3-year-old girl presents with fever and a stiff neck. CSF shows acid-fast bacilli. Most likely diagnosis is:

Correct Answer: C

Rationale: TB meningitis features stiff neck and acid-fast bacilli, per CDC. A, B, D, E differ in CSF.

Question 3 of 5

A 4-year-old girl presents with fever and swollen hands. Exam shows conjunctivitis and a rash. Most likely diagnosis is:

Correct Answer: B

Rationale: Kawasaki disease includes fever, swollen hands, conjunctivitis, and rash, per AHA. A, C-E differ.

Question 4 of 5

Most common cause of delayed puberty in girls is:

Correct Answer: A

Rationale: Turner syndrome is the most common cause of delayed puberty in girls, per AAP (doc p148, Q565).

Question 5 of 5

A newborn appears with prolonged jaundice, umbilical hernia, and large fontanelles. Labs reveal elevated TSH and low T4. Most likely diagnosis is:

Correct Answer: B

Rationale: Congenital hypothyroidism fits jaundice, hernia, large fontanelles, and abnormal thyroid labs, per AAP (doc p149, Q581).

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