A 30-year-old woman on propylthiouracil with fever, sore throat. Most important initial step?

Correct Answer: C

Rationale: The most important initial step in a 30-year-old woman on propylthiouracil with fever and sore throat is to perform a CBC. This is crucial to assess for potential agranulocytosis, a rare but serious side effect of propylthiouracil leading to severe neutropenia. A CBC will reveal any abnormalities in white blood cell counts, particularly neutrophils, guiding immediate management. Checking serum TSH or T3 levels is not necessary in this acute situation and won't provide immediate actionable information. A chest x-ray is not indicated unless there are specific respiratory symptoms or clinical signs suggesting a need for imaging.

Correct Answer: C

Rationale: The correct answer is C because taking aspirin can worsen thrombocytopenia by further reducing platelet function, leading to increased risk of bleeding. Aspirin is a known blood thinner and can exacerbate the condition in a patient with low platelet count. Choices A, B, and D are not as concerning because bruising easily, soft dark bowel movements, and decreased appetite can be common side effects of chemotherapy and not directly related to worsening thrombocytopenia.

Correct Answer: A

Rationale: Correct Answer: A Rationale: 1. Administering oral cyclosporine is crucial for managing GVHD post-transplant. 2. Cyclosporine suppresses the immune response, reducing GVHD symptoms. 3. It is essential to maintain therapeutic drug levels for efficacy. 4. Assessing for infection signs (Choice B) and educating about infection prevention (Choice D) are important but not the immediate priority. 5. Infusing D5NS at 125 mL/hr (Choice C) is not indicated for GVHD management.

Correct Answer: C

Rationale: The correct answer is C: SS. In sickle cell anemia, the genetic pattern is homozygous for the sickle cell gene (HbS), resulting in the genotype SS. This means both copies of the hemoglobin gene are mutated, leading to the production of abnormal hemoglobin. Choice A (AS) indicates a carrier of the sickle cell trait with one normal and one mutated gene. Choice B (AA) represents a normal individual with two normal hemoglobin genes. Choice D (AF) is an incorrect combination as there is no such genetic pattern associated with sickle cell anemia.

Correct Answer: D

Rationale: The correct answer is D because Hodgkin lymphoma B symptoms include all of the above. A - Loss of weight can be a symptom due to metabolic changes. B - Drenching night sweats are common in Hodgkin lymphoma. C - Fever without infection is a classic B symptom. Therefore, all three symptoms are characteristic of Hodgkin lymphoma B symptoms.