A 30-year-old man has an ejection fraction of 0.25 and an end systolic volume of 150 ml. What is his end-diastolic volume?

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Question 1 of 5

A 30-year-old man has an ejection fraction of 0.25 and an end systolic volume of 150 ml. What is his end-diastolic volume?

Correct Answer: D

Rationale: Ejection fraction = SV/EDV; SV = EDV - ESV. Given EF = 0.25 and ESV = 150 ml, SV = 50 ml, so EDV = 200 ml.

Question 2 of 5

Which of the following is unable to protect the cell against free radical damage?

Correct Answer: B

Rationale: Xanthine oxidase generates free radicals, unlike the others which neutralize them.

Question 3 of 5

A 50-year-old man with a lengthy history of diabetes mellitus and hypertension has had pain in the left shoulder and arm for the past 12 hours. Over the next 6 hours, he develops shortness of breath, which persists for 2 days. On day 3, he visits the physician. On physical examination, his blood pressure is 160/100 mm Hg. Laboratory studies show that the total creatine kinase (CK) activity is within reference range, but the troponin I level is elevated. The patient is admitted to the hospital and continues to experience dyspnea for the next 3 days. On day 7 after the onset of shoulder pain, he has a cardiac arrest. Postmortem examination shows a large transmural infarction of the left anterior free wall with rupture and hemopericardium. Which of the following statements is best supported by these clinical and autopsy data?

Correct Answer: C

Rationale: Elevated troponin I on day 3 indicates an infarction began on day 1, supported by the autopsy findings.

Question 4 of 5

Which one of the following is correct regarding alpha-adrenergic blockers?

Correct Answer: B

Rationale: Alpha-blockers like tamsulosin treat benign prostatic hyperplasia by relaxing smooth muscle.

Question 5 of 5

Which of the following could cause reflex tachycardia and/or postural hypotension on initial administration?

Correct Answer: D

Rationale: Prazosin, an alpha-blocker, causes reflex tachycardia and postural hypotension.

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