A 3-month-old infant presents with seizures and hypotonia. MRI shows lissencephaly. Most likely diagnosis is:

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Pediatric Gi Disorders Practice Questions Questions

Question 1 of 5

A 3-month-old infant presents with seizures and hypotonia. MRI shows lissencephaly. Most likely diagnosis is:

Correct Answer: D

Rationale: Lissencephaly syndrome causes seizures and smooth brain, per NORD. A-C, E differ.

Question 2 of 5

A 6-month-old infant presents with poor feeding and cyanosis. Echocardiogram shows hypoplastic left heart syndrome. The next step is:

Correct Answer: B

Rationale: Prostaglandin E1 stabilizes HLHS by maintaining ductal flow, per AHA. A, C-E follow.

Question 3 of 5

A 3-month-old infant presents with seizures and microcephaly. MRI shows calcifications. Most likely diagnosis is:

Correct Answer: B

Rationale: Congenital CMV causes seizures and calcifications, per CDC. A, C-E differ.

Question 4 of 5

A 3-year-old girl presents with fever and a stiff neck. CSF shows gram-negative coccobacilli. Most likely diagnosis is:

Correct Answer: B

Rationale: H. influenzae meningitis fits gram-negative coccobacilli, per AAP. A, C-E differ.

Question 5 of 5

A 5-year-old boy presents with fever and a petechial rash. Labs show thrombocytopenia and elevated D-dimer. Most likely diagnosis is:

Correct Answer: C

Rationale: DIC fits petechiae and elevated D-dimer, per ISTH. A, B, D, E differ.

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