A 28 year old woman with cystic fibrosis presents with increasing shortness of breath and production of abundant foul-smelling sputum. The sputum in this patient is most likely associated with which of the following pulmonary condition?

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Question 1 of 5

A 28 year old woman with cystic fibrosis presents with increasing shortness of breath and production of abundant foul-smelling sputum. The sputum in this patient is most likely associated with which of the following pulmonary condition?

Correct Answer: B

Rationale: Bronchiectasis (B) links to cystic fibrosis sputum . CFTR mutation thickens mucus , dilating bronchi (100 mL/day). Atelectasis (A) collapses. Emphysema (C) is dry. Pneumothorax (D) lacks sputum. B's infection unlike C's dryness is typical, per document.

Question 2 of 5

Most of the oxygen being transported by blood:

Correct Answer: C

Rationale: Oxygen is reversibly bound to haemoglobin (C) . Haemoglobin in RBCs (5 billion/mL) carries 98% of O2 (20 mL/dL), binding 4 molecules/O2 via iron. Plasma (A) holds 2%. Glucose (B) isn't an O2 carrier. Heartbeat energy (D) uses ATP, not O2 directly. C's capacity unlike A's minor role ensures tissue delivery, per physiology.

Question 3 of 5

In the presence of active surfactants, all of the following are expected to decrease EXCEPT?

Correct Answer: B

Rationale: Surfactant lowers alveolar surface tension (C) from 30 dynes/cm to 5, reducing collapse tendency (A) and work of breathing. Lung compliance (B) increases (normal 0.2 L/cm H2O to 0.5), not decreases, as expansion eases. In 300 million alveoli, surfactant's dipalmitoylphosphatidylcholine stabilizes, countering Laplace's law (P = 2T/r). B's rise unlike A's or D's fall enhances ventilation efficiency, per physiology (Q29).

Question 4 of 5

Which of the following is the most factor that can increase the volume of air entering the lung?

Correct Answer: A

Rationale: Pressure gradient (A) drives air into lungs . Inspiration drops intrapulmonary pressure (e.g., -1 mmHg below atmospheric, 760 mmHg), via diaphragm contraction (Q22). A 2 mmHg gradient moves ~500 mL (Vt). Action potentials (B) initiate muscle firing, but gradient magnitude not nerve signal strength dictates volume (Boyle's law: P1V1 = P2V2). C overcomplicates A alone suffices. D reduces flow. A's primacy unlike B's indirect role governs ventilation, per respiratory mechanics.

Question 5 of 5

If dead space is one third of the tidal volume and arterial PCO2 is 45 mmHg, what is the mixed expired PCO2?

Correct Answer: B

Rationale: Mixed expired PCO2 (PECO2) is 30 mmHg. If Vd = Vt/3, then Va = 2Vt/3. Bohr's equation: Vd/Vt = (PaCO2 - PECO2) / PaCO2. Given PaCO2 = 45 mmHg, Vd/Vt = 1/3 → 1/3 = (45 - PECO2) / 45 → PECO2 = 45 - 15 = 30 mmHg. PECO2 reflects alveolar (40 mmHg) and dead space (0 mmHg) mix. B's 30 unlike A's 20 or D's 45 fits 1/3 dead space dilution, per gas mixing physiology (Q12).

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