A 2-year-old boy presents with developmental delay and coarse facial features. Urine shows increased glycosaminoglycans. Most likely diagnosis is:

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Question 1 of 5

A 2-year-old boy presents with developmental delay and coarse facial features. Urine shows increased glycosaminoglycans. Most likely diagnosis is:

Correct Answer: B

Rationale: Mucopolysaccharidosis features coarse facies and glycosaminoglycan buildup, per NORD. A, C-E have distinct phenotypes.

Question 2 of 5

A 5-year-old boy presents with difficulty walking and muscle weakness. Creatine kinase is 10,000 U/L. Most likely diagnosis is:

Correct Answer: B

Rationale: Duchenne muscular dystrophy features weakness and high CK in boys, per MDA. A, C-E have lower CK.

Question 3 of 5

A 3-year-old girl presents with a barking cough and inspiratory stridor. Symptoms improve with cool mist. Most likely diagnosis is:

Correct Answer: B

Rationale: Croup presents with barking cough and stridor, responsive to cool mist, per AAP. A, C-E differ in symptoms.

Question 4 of 5

A 3-year-old girl presents with fever and a stiff neck. CSF shows acid-fast bacilli. Most likely diagnosis is:

Correct Answer: C

Rationale: TB meningitis features stiff neck and acid-fast bacilli, per CDC. A, B, D, E differ in CSF.

Question 5 of 5

A 4-year-old girl presents with fever and swollen hands. Exam shows conjunctivitis and a rash. Most likely diagnosis is:

Correct Answer: B

Rationale: Kawasaki disease includes fever, swollen hands, conjunctivitis, and rash, per AHA. A, C-E differ.

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