A 2-month-old boy appears with chronic cough and failure to thrive. Physical examination reveals bilateral coarse crackles and clubbing. Sweat chloride test is positive. Most likely diagnosis is:

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Question 1 of 5

A 2-month-old boy appears with chronic cough and failure to thrive. Physical examination reveals bilateral coarse crackles and clubbing. Sweat chloride test is positive. Most likely diagnosis is:

Correct Answer: D

Rationale: Cystic fibrosis fits chronic cough, failure to thrive, crackles, clubbing, and positive sweat test, per CFF. A-C, E don’t match.

Question 2 of 5

Most common musculoskeletal abnormality in patients with cystic fibrosis is:

Correct Answer: A

Rationale: Osteoporosis is the most common musculoskeletal issue in cystic fibrosis, from malabsorption, per CFF. B-E are less frequent.

Question 3 of 5

A 4-month-old infant presents with watery diarrhea and dehydration. Stool culture grows Vibrio cholerae. The best treatment is:

Correct Answer: C

Rationale: Oral rehydration solution is the cornerstone for cholera, per WHO, correcting dehydration. A, B, D, E are adjunctive or contraindicated.

Question 4 of 5

A 3-year-old girl presents with a high fever and drooling. X-ray shows a thumbprint sign. Most likely diagnosis is:

Correct Answer: B

Rationale: Epiglottitis presents with fever, drooling, and a thumbprint sign, per AAP. A, C-E have different signs.

Question 5 of 5

A 6-month-old infant presents with poor feeding and hypotonia. Exam shows hepatomegaly and hypoglycemia. Most likely diagnosis is:

Correct Answer: A

Rationale: Glycogen storage disease causes hypotonia, hepatomegaly, and hypoglycemia, per NORD. B-E differ in presentation.

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