58 y/o male presents with diarrhea. His evaluation is positive for Tissues Transglutaminase Ab. He underwent EGD with small bowel biopsy which was consistent with celiac disease. Colonoscopy was normal. Labs: Hgb I I (MCV 72), Ferritin I 2, Alk Phos 2-fold elevation, Normal AST/ALTI Bilirubin/ GGT. Fasting glucose I04. What additional testing would you recommend?

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Question 1 of 5

58 y/o male presents with diarrhea. His evaluation is positive for Tissues Transglutaminase Ab. He underwent EGD with small bowel biopsy which was consistent with celiac disease. Colonoscopy was normal. Labs: Hgb I I (MCV 72), Ferritin I 2, Alk Phos 2-fold elevation, Normal AST/ALTI Bilirubin/ GGT. Fasting glucose I04. What additional testing would you recommend?

Correct Answer: D

Rationale: Celiac disease causes malabsorption, often leading to vitamin D deficiency, which can explain the elevated Alk Phos (bone turnover) and anemia. Checking 25-hydroxy vitamin D is recommended to assess and manage this common complication.

Question 2 of 5

34 yo woman with history of a miscarriage 5 years ago presents with new right-sided hemiparesis and slurred speech for the past 2 hours Her symptoms slowly resolve while in the emergency department.

Correct Answer: D

Rationale: After a TIA, checking for both Protein C/S deficiencies and antiphospholipid antibodies is important to determine underlying hypercoagulable states.

Question 3 of 5

All are true except:

Correct Answer: A

Rationale: Serum M protein may be absent in non-secretory myeloma. Bence Jones proteins vary, bone scans miss lytic lesions (X-rays are better), and erythropoietin isn't first-line for all MDS.

Question 4 of 5

True or false: Initial treatment regimens for community-acquired pneumonia are empiric and epidemiological and clinical clues should be considered when selecting an empiric regimen.

Correct Answer: A

Rationale: This statement is true because initial treatment for community-acquired pneumonia is empiric, relying on epidemiological patterns and clinical presentation to guide antibiotic selection.

Question 5 of 5

A 36-year-old male was injured in a high-speed motor accident. He is unbelted and, as a result, was ejected from vehicle. On arrival to the trauma bay. His GCS scale was 7 leading to emergently intubated. Injuries included moderate subdural hematoma and subarachnoid hemorrhage. Multiple bilateral nondisplaced rib fractures, bilateral pulmonary contusions, grade 3 splenic injury managed non-operatively and left femur fracture managed with an intramedullary rod on postoperative day 6. On post-trauma day 9, his GCS score is 11T and he qualifies for extubation. Which of the following criteria for extubation is best supported by the literature?

Correct Answer: C

Rationale: A successful spontaneous breathing trial (SBT) of 30 minutes is the most evidence-based criterion for predicting successful extubation, as it assesses the patient's ability to breathe independently. Studies, including those in critical care literature, show SBT outperforms other measures like negative inspiratory force or cuff leak in multi-trauma patients.

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