22-year-old with stage I Hodgkin disease says, 'I’m afraid of dying.' Best response?

Correct Answer: C

Rationale: The correct answer is C because it demonstrates active listening and empathy, allowing the patient to express their concerns fully. By saying "Tell me more about your fear," the healthcare provider acknowledges the patient's feelings and opens up a dialogue to address their specific worries. This approach can help build trust and rapport, leading to a more effective therapeutic relationship. Choice A is incorrect as it generalizes the patient's fear without addressing the individual's concerns. Choice B is also incorrect as it jumps to suggesting medication without fully understanding the root of the patient's fear. Choice D, although true, does not directly address the patient's emotional needs or provide support in coping with their fear of dying.

Correct Answer: B

Rationale: Rationale: Von Willebrand factor plays a crucial role in primary hemostasis by binding platelets to the subendothelium at sites of vascular injury, facilitating platelet adhesion and aggregation. This is important for forming a platelet plug to stop bleeding. Choices A and C are incorrect because von Willebrand factor does not directly bind platelets to each other or to a phospholipid surface. Choice D is incorrect because von Willebrand factor does not carry factor VII, but it does carry factor VIII.

Correct Answer: C

Rationale: The correct answer is C: Reed-Sternberg cell. These large, abnormal cells are characteristic of Hodgkin lymphoma. They originate from B cells but have lost most B cell markers. They express CD30 and CD15. A is incorrect as Hodgkin lymphoma is not derived from cytotoxic T cells. B is incorrect as it is not a malignancy involving NK cells. D is incorrect as Hodgkin lymphoma does not involve CD33+ clonal B cells.

Correct Answer: C

Rationale: The correct answer is C, Factor VIII. Vitamin K deficiency primarily affects the synthesis of Factors II, VII, IX, and X. Factor VIII is not dependent on vitamin K for its synthesis since it is a co-factor for Factor IX. Therefore, Factor VIII levels remain unaffected in Vitamin K deficiency. Factors II, VII, and IX are all vitamin K-dependent factors, making them incorrect choices.

Correct Answer: A

Rationale: Correct Answer: A - Low TIBC Rationale: - Pallor, fatigue, koilonychias, and cheilosis are symptoms of iron deficiency anemia. - Low TIBC is not an expected lab finding in iron deficiency anemia. - TIBC measures the total amount of iron that can be carried in the blood by transferrin. In iron deficiency anemia, TIBC is typically elevated, not low. - High serum transferrin, low iron:TIBC ratio, and low serum ferritin are all expected lab findings in iron deficiency anemia indicating low iron stores and increased iron-binding capacity.