ATI LPN
NCLEX PN Pharmacology Practice Questions Questions
Question 1 of 9
Drugs that may cause increased adverse effects in children include:
Correct Answer: B
Rationale: Choice B is correct because tetracycline causes tooth discoloration and bone growth issues in children under 8, a significant ADR, unlike others. Choice A is incorrect as acetaminophen is safe at proper doses with minimal ADRs. Choice C is wrong because amoxicillin's ADRs (e.g., rash) are mild and manageable. Choice D is incorrect since only tetracycline poses a notable risk.
Question 2 of 9
A client asks the NP about the differences in drug effects between men and women. What is known about the differences between the pharmacokinetics of men and women?
Correct Answer: C
Rationale: Choice C is correct because women generally have a higher percentage of body fat, affecting the volume of distribution for lipophilic drugs, a key pharmacokinetic difference. Choice A is incorrect as body temperature differences are minimal and don't significantly alter pharmacokinetics. Choice B is wrong because men, not women, typically have greater muscle mass. Choice D is incorrect since subjective factors aren't proven pharmacokinetic variables.
Question 3 of 9
Drugs that may cause gynecomastia in men include:
Correct Answer: A
Rationale: Choice A is correct because spironolactone blocks androgen receptors, causing gynecomastia, a well-documented side effect. Choice B is incorrect as atenolol (beta blocker) rarely causes it. Choice C is wrong because lisinopril (ACE inhibitor) doesn't typically lead to gynecomastia. Choice D is incorrect since only spironolactone is a clear culprit.
Question 4 of 9
The primary care NP is performing a physical examination on a 6-month-old infant with cerebral palsy who has not had previous immunizations. The NP plans to begin vaccinations and should include:
Correct Answer: A
Rationale: The correct answer is A because infants with stable neurologic conditions like cerebral palsy should receive DTaP. Choice B is incorrect (TdaP for adults). Choice C is wrong (TD incomplete). Choice D is inaccurate (tetanus alone insufficient).
Question 5 of 9
Herbal products that should be avoided when a patient is prescribed an antidepressant include:
Correct Answer: B
Rationale: Choice B is correct because St John's wort induces CYP3A4 and affects serotonin, risking reduced antidepressant efficacy or serotonin syndrome, so it's to be avoided. Choice A is incorrect as ginkgo biloba doesn't significantly interact with antidepressants. Choice C is wrong because valerian root's sedative effect is minor and not a major concern. Choice D is incorrect since only St John's wort poses a substantial risk.
Question 6 of 9
The major reason for not crushing a sustained-release capsule is that, if crushed, the coated beads of the drugs could possibly result in:
Correct Answer: B
Rationale: Choice B is correct because crushing a sustained-release capsule releases all drug at once, bypassing controlled release, which can lead to toxic levels quickly. Choice A is incorrect as disintegration isn't harmful itself, just alters release. Choice C is wrong because malabsorption isn't the primary risk—overdose is. Choice D is incorrect since deterioration implies drug degradation, not the immediate danger of crushing.
Question 7 of 9
A patient has begun treatment for HIV. The primary care NP should monitor the patient's complete blood count (CBC) at least every __ months.
Correct Answer: B
Rationale: The correct answer is B because CBC monitoring every 3-6 months checks for toxicity, more if values are low. Choices A, C, and D are incorrect (outside standard range).
Question 8 of 9
A 23-year-old woman who is sexually active has an abnormal Pap smear. She asks the primary care NP about the human papillomavirus vaccine (HPV). The NP should recommend:
Correct Answer: C
Rationale: The correct answer is C because women 13-26 should get the three-dose HPV series, even with abnormal Pap. Choice A is incorrect (vaccine still beneficial). Choice B is wrong (single dose insufficient). Choice D is inaccurate (partner not the focus).
Question 9 of 9
Drugs that require a REMS program include:
Correct Answer: B
Rationale: Choice B is correct because isotretinoin requires a REMS due to teratogenicity, involving strict pregnancy prevention measures, unlike others. Choice A is incorrect as acetaminophen lacks serious enough risks for REMS. Choice C is wrong because ibuprofen's OTC status and safety profile don't warrant REMS. Choice D is incorrect since only isotretinoin applies.