ATI LPN
LPN Pharmacology Multiple Choice Questions Questions
Question 1 of 9
Drugs that are prone to cause adverse drug effects include:
Correct Answer: C
Rationale: Choice C is correct because insulins have a narrow therapeutic index, making ADRs like hypoglycemia common if dosing is off, a high-risk profile. Choice A is incorrect as diuretics' ADRs (e.g., electrolyte imbalance) are manageable, less prone. Choice B is wrong because inhaled anticholinergics have fewer systemic effects. Choice D is incorrect since stimulants' ADRs are notable but less frequent than insulin's.
Question 2 of 9
An NP orders an inhaled corticosteroid 2 puffs twice daily and an albuterol metered-dose inhaler 2 puffs every 4 hours as needed for cough or wheezing for a 65-year-old patient with recent onset of reactive airways disease who reports symptoms occurring every 1 or 2 weeks. At a follow-up appointment several months later, the patient reports no change in frequency of symptoms. The NP's initial action should be to:
Correct Answer: C
Rationale: The correct answer is C because assessing medication use ensures compliance and correct technique before further interventions. Choice A is incorrect as spirometry isn’t the first step. Choice B is wrong since systemic steroids aren’t initial. Choice D is inaccurate as education follows compliance check.
Question 3 of 9
Drugs that may require weight-based dosing in children include:
Correct Answer: D
Rationale: Choice D is correct because acetaminophen, aspirin, and codeine all require weight-based dosing in children to ensure safety and efficacy, as pediatric pharmacokinetics vary by body weight. Choice A is incorrect alone as it's one example. Choice B is wrong by itself because aspirin, though avoided, uses weight when needed. Choice C is incorrect solo since codeine also requires it despite restrictions.
Question 4 of 9
Michael is on warfarin and has recently been found to have a genetic variation that increases his sensitivity to warfarin. His dose may need to be:
Correct Answer: B
Rationale: Choice B is correct because a genetic variation (e.g., CYP2C9 or VKORC1 polymorphism) increasing warfarin sensitivity means less drug is needed to achieve anticoagulation, so the dose should be decreased to avoid bleeding risks. Choice A is incorrect as increasing the dose would heighten toxicity. Choice C is wrong because holding it entirely risks under-treatment, not adjustment. Choice D is incorrect since unchanged dosing ignores the genetic impact.
Question 5 of 9
An important difference between physician assistants (PAs) and NPs is PAs:
Correct Answer: A
Rationale: The correct answer is A because PAs typically require physician supervision. Choice B is incorrect as they must follow protocols. Choice C is wrong since co-signatures don’t cover all categories universally. Choice D is inaccurate as PAs lack independent authority.
Question 6 of 9
Requirements for generic drugs include:
Correct Answer: A
Rationale: Choice A is correct because the FDA mandates generics have the same active ingredient, dosage, and route as brand-name drugs for bioequivalence. Choice B is incorrect as cost isn't a requirement—it varies. Choice C is wrong because color isn't regulated. Choice D is incorrect since only A is required.
Question 7 of 9
Patient education about vaccines should include:
Correct Answer: D
Rationale: Choice D is correct because educating on side effects (e.g., soreness), series completion (full immunity), and contraindications (e.g., allergies) ensures safe vaccination, per CDC advice. Choice A is incorrect alone as it's one aspect. Choice B is wrong by itself because completion is just part. Choice C is incorrect solo since contraindications are only one element.
Question 8 of 9
Criteria for choosing an effective drug for a disorder include:
Correct Answer: B
Rationale: Choice B is correct because nationally recognized guidelines provide evidence-based recommendations for effective drug selection, ensuring treatment aligns with proven standards. Choice A is incorrect as patient preference alone lacks scientific basis and could lead to suboptimal therapy. Choice C is wrong because basing decisions on sample availability prioritizes convenience over clinical appropriateness. Choice D is also incorrect since DEA guidelines focus on controlled substances, not general criteria for selecting effective drugs for disorders.
Question 9 of 9
Drugs that should be stored at room temperature include:
Correct Answer: D
Rationale: Choice D is correct because aspirin, lorazepam, and metformin are stable at room temperature (15-30°C) and don't require special storage, per USP standards. Choice A is incorrect alone as it's one drug. Choice B is wrong by itself because lorazepam is just part. Choice C is incorrect solo since metformin is only one agent.