ATI LPN
LPN Nursing Questions Related to Pharmacology Questions
Question 1 of 9
Clinical judgment in prescribing includes:
Correct Answer: S
Rationale: Choice A is correct because clinical judgment involves balancing efficacy, safety, and cost to ensure patients can afford and adhere to treatment, which is critical for successful outcomes. Choice B is incorrect as always choosing the newest medication ignores evidence-based practice; newer drugs may lack long-term data or be unnecessarily expensive. Choice C is wrong because distributing samples isn't a sustainable prescribing strategy and may not meet ongoing needs. Choice D is also incorrect since mandating generics could compromise efficacy if a brand-name drug is clinically necessary.
Question 2 of 9
Women who are prescribed drugs that are known teratogens should:
Correct Answer: A
Rationale: Choice A is correct because teratogenic drugs can harm a fetus, so effective contraception is essential to prevent pregnancy during treatment, per safety guidelines. Choice B is incorrect as breastfeeding avoidance applies post-delivery, not during prescribing. Choice C is wrong because increasing vitamins doesn't mitigate teratogenic risk. Choice D is incorrect since only contraception directly addresses the primary risk.
Question 3 of 9
Drugs that may cause increased adverse effects in women include:
Correct Answer: B
Rationale: Choice B is correct because women's lower lean mass reduces the volume of distribution for water-soluble drugs, increasing concentrations and ADR risk. Choice A is incorrect as lipid-soluble drugs distribute more in fat, not necessarily causing more ADRs. Choice C is wrong because protein binding isn't sex-specific enough here. Choice D is incorrect since only water-soluble drugs align.
Question 4 of 9
Which of the following statements about the major distribution barriers (blood-brain or fetal-placental) is true?
Correct Answer: B
Rationale: Choice B is correct because the blood-brain barrier, with its tight junctions, slows entry of many drugs, especially water-soluble ones, protecting the brain. Choice A is incorrect as water-soluble, ionized drugs cross poorly due to barrier selectivity. Choice C is wrong because the fetal-placental barrier doesn't fully block drugs—many cross and affect the fetus. Choice D is incorrect since lipid-soluble drugs readily pass these barriers, posing risks in pregnancy.
Question 5 of 9
Clinical judgment in prescribing includes:
Correct Answer: S
Rationale: Choice A is correct because clinical judgment involves balancing efficacy, safety, and cost to ensure patients can afford and adhere to treatment, which is critical for successful outcomes. Choice B is incorrect as always choosing the newest medication ignores evidence-based practice; newer drugs may lack long-term data or be unnecessarily expensive. Choice C is wrong because distributing samples isn't a sustainable prescribing strategy and may not meet ongoing needs. Choice D is also incorrect since mandating generics could compromise efficacy if a brand-name drug is clinically necessary.
Question 6 of 9
The current trend toward transitioning NP programs to the doctoral level will mean that:
Correct Answer: C
Rationale: The correct answer is C because doctoral programs aim to better prepare NPs for evolving healthcare needs, per the AACN. Choice A is incorrect as licensure remains state-specific. Choice B is wrong since prescriptive authority depends on state laws. Choice D is inaccurate as supervision rules vary by state.
Question 7 of 9
An 80-year-old patient who has COPD takes TMP/SMX for acute exacerbations, which occur three or four times each year. To monitor this patient for adverse drug reactions, the primary care NP should order:
Correct Answer: D
Rationale: The correct answer is D because elderly patients on TMP/SMX risk bone marrow suppression, monitored via CBC. Choice A is incorrect (liver tests pre-treatment). Choice B is wrong (renal pre-treatment). Choice C is inaccurate (bilirubin not primary).
Question 8 of 9
Which of the following statements about the major distribution barriers (blood-brain or fetal-placental) is true?
Correct Answer: B
Rationale: Choice B is correct because the blood-brain barrier, with its tight junctions, slows entry of many drugs, especially water-soluble ones, protecting the brain. Choice A is incorrect as water-soluble, ionized drugs cross poorly due to barrier selectivity. Choice C is wrong because the fetal-placental barrier doesn't fully block drugs—many cross and affect the fetus. Choice D is incorrect since lipid-soluble drugs readily pass these barriers, posing risks in pregnancy.
Question 9 of 9
Herbal products that may increase INR include:
Correct Answer: A
Rationale: Choice A is correct because ginkgo biloba can increase INR by enhancing warfarin's effect through antiplatelet activity, risking bleeding. Choice B is incorrect as St John's wort induces CYP2C9, decreasing INR and warfarin efficacy. Choice C is wrong because valerian root doesn't significantly alter INR. Choice D is incorrect since only ginkgo biloba increases INR.