A 15-year-old boy recently immigrated into America. He has an outgoing 'cocktail party' personality but also seems nervous. He appears with an elongated face, full cheeks, and thicker lips but a decrease in both the periorbital fullness. Most likely diagnosis is:

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Question 1 of 5

A 15-year-old boy recently immigrated into America. He has an outgoing 'cocktail party' personality but also seems nervous. He appears with an elongated face, full cheeks, and thicker lips but a decrease in both the periorbital fullness. Most likely diagnosis is:

Correct Answer: B

Rationale: Williams syndrome fits the 'cocktail party' personality, facial features, and anxiety (NIH). A, C-E don’t match this profile.

Question 2 of 5

Most common cause of massive hemoptysis in patients with cystic fibrosis is:

Correct Answer: B

Rationale: Bronchial artery bleeding causes massive hemoptysis in cystic fibrosis, per CFF, due to eroded vessels. A, C-E are less likely.

Question 3 of 5

A 2-month-old boy appears with failure to thrive and steatorrhea. Physical examination reveals bilateral coarse crackles. Sweat chloride test is positive. Most likely diagnosis is:

Correct Answer: D

Rationale: Cystic fibrosis matches failure to thrive, steatorrhea, crackles, and positive sweat test, per CFF. A-C, E don’t fit.

Question 4 of 5

A child with a history of cystic fibrosis appears with abdominal pain and constipation. Abdominal x-ray reveals fecal impaction in the rectosigmoid colon. Most likely diagnosis is:

Correct Answer: C

Rationale: Distal intestinal obstruction syndrome fits pain, constipation, and impaction in cystic fibrosis, per CFF. A, B, D, E differ.

Question 5 of 5

A 5-year-old boy presents with petechiae and bruising after a viral illness. Platelet count is 20,000/mm³. Most likely diagnosis is:

Correct Answer: C

Rationale: ITP follows viral illness with isolated thrombocytopenia, per ASH guidelines. A, B, D, E involve other abnormalities.

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