PN Pharmacology 2023 | Nurselytic

Correct Answer: C

Rationale: The correct response is C: "You will need to wait a couple of weeks to feel the therapeutic effect of the medication." Amitriptyline, a tricyclic antidepressant, often takes 2-4 weeks to reach its full therapeutic effect. This is due to the time required for the medication to build up in the body and for the brain chemistry to adjust. It is crucial for the nurse to educate the client about this delayed onset of action to manage their expectations and prevent premature discontinuation.


Choices A, B, and D are incorrect because they do not address the pharmacokinetics or expected timeline for amitriptyline to take effect. Informing the provider for a different medication, taking on an empty stomach, or increasing the dose may not be necessary or safe without giving the current medication adequate time to work. The nurse should prioritize patient education on the medication's expected timeline rather than making immediate changes.

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