ATI LPN
ATI LPN Pharmacology Quiz Questions
Extract:
Question 1 of 5
Drug therapy of tuberculosis differs from that of most other infections because:
Correct Answer: C
Rationale: Mycobacteria have a complex, impermeable cell wall, necessitating prolonged treatment with specialized drugs. TB therapy is longer than most infections, patients often have symptoms, and drugs treat both active and latent disease.
Question 2 of 5
Acquired resistance is:
Correct Answer: D
Rationale: Acquired resistance occurs when microbes develop mechanisms to evade antibiotics after exposure, rendering drugs ineffective. The other options describe antibiotics, pathogenicity, or virulence, not resistance.
Question 3 of 5
A nurse is preparing to administer vitamin K 1 mg IM to a newborn. Available is vitamin K injection 1 mg/0.5 mL. How many mL should the nurse administer per dose? (Round the answer to the nearest tenth. Use a leading zero if it applies. Do not use a trailing zero.)
Correct Answer: 0.5
Rationale: Using the formula: Volume (mL) = Dose (mg) ÷ Concentration (mg/mL), and noting concentration is 1 mg/0.5 mL (or 2 mg/mL), for a 1 mg dose, Volume = 1 ÷ 2 = 0.5 mL, which is already to the nearest tenth.
Question 4 of 5
The term 'mutations' refers to:
Correct Answer: B
Rationale: Mutations are permanent, inheritable DNA changes that can alter organism traits, including drug resistance. Other options describe pathogens, antibiotics, or virulence, not mutations.
Question 5 of 5
A patient at a rehabilitation center is prescribed erythromycin. The nurse is reviewing the patient's medication list, checking to see if there are medications that should not be taken with this antibiotic. One medication is found. What medication should not be taken with erythromycin?
Correct Answer: A
Rationale: Erythromycin inhibits the metabolism of statins like lovastatin by affecting the CYP3A4 enzyme, increasing the risk of myopathy and rhabdomyolysis. Lasix, ibuprofen, and lisinopril have no significant interactions with erythromycin, making them safe to co-administer.