ATI LPN
ATI LPN Pharmacology Quiz Questions
Extract:
Question 1 of 5
A patient at a rehabilitation center is prescribed erythromycin. The nurse is reviewing the patient's medication list, checking to see if there are medications that should not be taken with this antibiotic. One medication is found. What medication should not be taken with erythromycin?
Correct Answer: A
Rationale: Erythromycin inhibits the metabolism of statins like lovastatin by affecting the CYP3A4 enzyme, increasing the risk of myopathy and rhabdomyolysis. Lasix, ibuprofen, and lisinopril have no significant interactions with erythromycin, making them safe to co-administer.
Question 2 of 5
A nurse is preparing to administer haloperidol 5 mg IM to a client. Available is haloperidol 50 mg/mL. How many mL should the nurse administer per dose? (Round the answer to the nearest tenth/whole number. Use a leading zero if it applies. Do not use a trailing zero.)
Correct Answer: 0.1
Rationale:
To calculate the volume of haloperidol to administer, use the formula: Volume (mL) = Dose (mg) ÷ Concentration (mg/mL). Given a dose of 5 mg and a concentration of 50 mg/mL, Volume = 5 ÷ 50 = 0.1 mL. The answer is rounded to the nearest tenth as instructed.
Question 3 of 5
Mrs. Oza, age 69, has hypertension and has one functioning kidney. She loves chocolates and enjoys an alcoholic beverage twice a week. Her hobby is gardening and she goes for long walks despite having arthritis. Which one of the following pieces of information is likely to have the greatest significance if she is prescribed vancomycin?
Correct Answer: C
Rationale: Vancomycin is excreted by the kidneys, and with only one functioning kidney, Mrs. Oza risks drug accumulation and toxicity unless the dose is adjusted. Alcohol, sun exposure, and hypertension are less critical for vancomycin management.
Question 4 of 5
A nurse is preparing to administer dexamethasone 3 mg PO. Available is dexamethasone 1.5 mg tablets. How many tablets should the nurse administer? (Round the answer to the nearest whole number. Use a leading zero if it applies. Do not use a trailing zero.)
Correct Answer: 2
Rationale:
To calculate the number of tablets, use the formula: Number of tablets = Dose (mg) ÷ Strength per tablet (mg). Given a dose of 3 mg and a tablet strength of 1.5 mg, Number of tablets = 3 ÷ 1.5 = 2 tablets. The answer is a whole number as required.
Question 5 of 5
Which class of antibiotic is associated with cartilage toxicity and rupture of the Achilles tendon?
Correct Answer: A
Rationale: Fluoroquinolones (e.g., ciprofloxacin) are linked to tendonitis and Achilles tendon rupture, particularly in older adults or with corticosteroid use, due to effects on connective tissue. Other classes listed do not have this association.