ATI PN Custom Pharmacology | Nurselytic

Questions 40

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ATI PN Custom Pharmacology Questions

Extract:


Question 1 of 5

Which effect of protein binding on drugs in the bloodstream is accurate?

Correct Answer: D

Rationale: The correct answer is D: Accumulation of the drug. Protein binding can decrease the amount of free drug available for distribution and metabolism, leading to increased drug levels in the bloodstream. This can result in drug accumulation and potential toxicity.
Choice A is incorrect because protein binding typically does not inactivate drugs.
Choice B is incorrect as protein binding does not directly increase the risk of allergic reactions.
Choice C is incorrect as protein binding does not cause precipitation of idiosyncratic reactions.

Question 2 of 5

Which phenomenon occurs in the body as a person ages?

Correct Answer: D

Rationale: The correct answer is D. Lean body mass decreases as a person ages due to factors like decreased physical activity and hormonal changes. This leads to a decline in muscle mass and bone density.
Choice A is incorrect as protein needs actually increase with age to support muscle maintenance.
Choice B is incorrect as total fat content tends to increase with age.
Choice C is incorrect as total body water typically decreases as aging progresses.

Question 3 of 5

Which symptom is the most common with a hypersensitivity reaction to a medication?

Correct Answer: A

Rationale: The correct answer is A: Urticaria. This is the most common symptom in a hypersensitivity reaction to medication due to the release of histamine, causing skin rash and itching. Vomiting (
B) and wheezing (
C) can occur but are less common. Anaphylaxis (
D) is a severe, life-threatening reaction that can include urticaria but is not the most common symptom.

Question 4 of 5

Which aspect of pharmacokinetics should the nurse be most concerned with when caring for a patient with abnormal functioning of hepatic enzymes?

Correct Answer: D

Rationale: The correct answer is D: Metabolism. When hepatic enzymes are abnormal, it affects the liver's ability to metabolize drugs. This can lead to drug toxicity or reduced drug effectiveness. The nurse should closely monitor drug dosages and frequency to prevent adverse effects. Absorption (
A) may be affected by liver dysfunction but is less critical than metabolism in this scenario. Distribution (
B) and Excretion (
C) are more related to renal function than hepatic enzymes. The other choices (E, F, G) are not applicable. In summary, impaired hepatic metabolism can significantly alter drug response, making it the primary concern for the nurse.

Question 5 of 5

Which factor associated with aging increases the risk of gastric irritation from nonsteroidal anti-inflammatory drugs (NSAIDS) in older adults?

Correct Answer: C

Rationale: The correct answer is C: Delayed gastric emptying. As individuals age, gastric motility decreases, leading to delayed gastric emptying. This delay in emptying the stomach can result in a longer exposure of the stomach lining to NSAIDs, increasing the risk of gastric irritation. Option A, decreased splanchnic blood flow, may impact drug absorption but is not directly related to gastric irritation. Option B, prolonged secretion of gastric acid, may exacerbate existing conditions but is not the primary factor increasing the risk of gastric irritation from NSAIDs in older adults. Option D, loss of cells from the gastric plexus, does not directly impact gastric emptying and is not the main factor contributing to increased risk of gastric irritation in this scenario.

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