ATI LPN
ATI PN Custom Pharmacology Questions
Extract:
Question 1 of 5
A nurse is preparing to administer cefazolin 1g intermittent IV bolus in 0.9% sodium chloride 250 mL over 30 min. The drop factor on the manual IV tubing is 10 gtt/mL. The nurse should set the manual IV flow rate to deliver how many gtt/min? (Round the answer to the nearest whole number. Use a leading zero if it applies. Do not use a trailing zero.)
Correct Answer: A
Rationale:
To calculate the IV flow rate, we first need to determine the total volume to be infused per minute. There are 250 mL to be infused over 30 minutes, which equals 8.33 mL/min. Next, convert mL to drops using the drop factor (10 gtt/mL), giving 83 gtt/min (8.33 mL/min x 10 gtt/mL = 83 gtt/min).
Therefore, the correct answer is A: 83 gtt/min.
Choices B-G are incorrect as they do not align with the calculated flow rate based on the given parameters.
Question 2 of 5
Which blood level is assessed to determine the amount of circulating medication in a patient?
Correct Answer: C
Rationale: The correct answer is C: Peak. Peak blood level is assessed to determine the highest concentration of medication in the patient's bloodstream after administration. This peak level indicates the maximum amount of drug available for therapeutic effects. Trough level (choice
A) is the lowest concentration before the next dose. Drug (choice
B) is too generic. Therapeutic (choice
D) is a broad term and not specific to assessing medication levels.
Question 3 of 5
A nurse is preparing to administer amoxicillin 350 mg PO. Available is amoxicillin 250 mg/5 mL. How many mL should the nurse administer? (Round to the nearest whole number.)
Correct Answer: A
Rationale:
To calculate the mL needed for the dose, we use the formula: Desired dose (350 mg) ÷ Stock dose (250 mg) × Volume of stock solution (5 mL). This gives us: 350 ÷ 250 = 1.4; 1.4 × 5 = 7 mL.
Therefore, the nurse should administer 7 mL of amoxicillin.
Choice A is correct as it follows the correct calculation method. Other choices are incorrect because they do not result from the accurate calculation based on the given information.
Question 4 of 5
Which statement indicates a correct understanding of topical drug absorption in a pediatric patient?
Correct Answer: D
Rationale:
Correct
Answer: D
Rationale: Infants wearing plastic-coated diapers are more susceptible to skin absorption due to occlusion by the diaper, leading to increased permeability of the skin and enhanced drug absorption. Plastic-coated diapers create a warm and moist environment that increases skin hydration, facilitating drug penetration. This is important for topical drug absorption in pediatric patients.
Summary:
A: Incorrect. Skin hydration does not solely determine the absorption of water-soluble drugs in pediatric patients.
B: Incorrect. Inflammation typically increases drug absorption rather than decreasing it.
C: Incorrect.
Topical administration may vary in effectiveness depending on factors like skin integrity and age.
D: Correct. The occlusive nature of plastic-coated diapers enhances skin absorption in infants.
E, F, G:
Choices not provided.
Question 5 of 5
A patient takes two medications. Drug A is taken once per day; drug B is taken every 8 hours. Which conclusion about drug A is correct?
Correct Answer: C
Rationale: The correct answer is C: Drug A has a longer half-life than drug B. The half-life of a drug is the time it takes for half of the drug to be eliminated from the body. Since drug A is taken once a day compared to drug B taken every 8 hours, drug A must have a longer half-life to maintain therapeutic levels in the body over a 24-hour period. This indicates that drug A stays in the body longer than drug B.
Choice A is incorrect as the therapeutic range is not determined by the dosing frequency.
Choice B is irrelevant to the dosing frequency of the drugs.
Choice D is incorrect as toxicity is not directly related to dosing frequency.