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MSC NCLEX Physiological Integrity Pharmacological and Parenteral Therapies Questions

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Question 1 of 5

Prior to administering filgrastim, the nurse reviews the laboratory report results for the 3-year-old who completed the second round of chemotherapy three weeks ago. Which finding indicates a therapeutic response to filgrastim?

Correct Answer: C

Rationale: A: The Hct of 31% is normal but is unaffected by filgrastim, a colony-stimulating factor. B: The eosinophil count of 6% is elevated (0 to 2% is normal) but is not related to filgrastim use. C: Filgrastim (Neupogen) is a colony-stimulating factor used to increase the production of WBCs in persons who have bone marrow depression from chemotherapy. D: The platelet count of 150,000/mm3 is normal but is not used to evaluate the therapeutic effectiveness of filgrastim.

Question 2 of 5

The clinic nurse is reviewing prescriptions with the parents of the school-aged child with newly diagnosed generalized contact dermatitis. Which prescription should the nurse question with the HCP?

Correct Answer: A

Rationale: A: Prednisone (Deltasone) would not be a first-line treatment for contact dermatitis, and its use should be questioned. Prednisone may be added later if the contact dermatitis has not resolved. B: Calamine lotion is used to promote drying and help relieve itching. C: Diphenhydramine (Benadryl) helps to relieve itching. D: Hydrocortisone cream is an anti-inflammatory agent used to treat contact dermatitis.

Question 3 of 5

The factor that most determines drug distribution is:

Correct Answer: A

Rationale: Drugs are distributed via the circulatory system. Adequate perfusion is necessary for distribution of a drug. The other choices are not as dependent on adequate perfusion.

Question 4 of 5

The nurse observes that the client being treated with antipsychotics is unsteady while standing and walking and that the client's hands are trembling slightly. What should the nurse do?

Correct Answer: A

Rationale: The client is experiencing extrapyramidal symptoms (EPS) of pseudoparkinsonism, requiring an antiparkinsonian agent like trihexyphenidyl.

Question 5 of 5

The client has been on vancomycin for three days. Which of the following symptoms is least concerning?

Correct Answer: B

Rationale: Vancomycin can cause ototoxicity, and tinnitus, vertigo, and nausea are symptoms of this condition. Headache is not typically associated with vancomycin's side effects.

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