NCLEX-PN
Health Promotion and Maintenance NCLEX Questions Questions
Extract:
Question 1 of 5
The chemotherapeutic DNA alkylating agents such as nitrogen mustards are effective because they:
Correct Answer: A
Rationale: Alkylating agents are highly reactive chemicals that introduce alkyl radicals into biologically active molecules and thereby prevent their proper functioning, replication, and transcription.
Choice 2 is incorrect because alkylating agents have numerous side effects including alopecia, nausea, vomiting, and myelosuppression.
Choice 3 is incorrect because nitrogen mustards have a broad spectrum of activity against chronic lymphocytic leukemia, non-Hodgkin's lymphoma, and breast and ovarian cancer, but they are effective chemotherapeutic agents because of DNA crosslinkage.
Choice 4 is incorrect because alkylating agents are non-cell-cycle-specific agents.
Question 2 of 5
Correct Answer:
Rationale:
Question 3 of 5
Correct Answer:
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Question 4 of 5
Correct Answer:
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Question 5 of 5
Correct Answer:
Rationale: