NCLEX-PN
PN Nclex Questions 2024 Questions
Extract:
Question 1 of 5
How can medication bound to protein affect drug availability?
Correct Answer: C
Rationale: Medication bound to protein reduces the availability of the drug to produce desired medicinal effects because only unbound drugs can effectively bind to active receptor sites. When a drug is bound to protein, it cannot bind with receptor sites, limiting its therapeutic impact.
Choice A is incorrect because drug availability is reduced when it is bound to protein.
Choice B is incorrect as rapid distribution to receptor sites is not possible if the drug is bound to protein and cannot bind with receptors.
Choice D is incorrect as metabolism does not increase when the drug is bound to protein; the liver first needs to separate the drug from the protein before metabolism can occur.
Question 2 of 5
Correct Answer:
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Question 3 of 5
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Question 4 of 5
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Question 5 of 5
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Rationale: