ATI LPN
Brunner & Suddarth's Textbook of Medical-Surgical Nursing 14e (Hinkle 2017)
Chapter 8 : Overview of Genetics and Genomics in Nursing Questions
Question 1 of 5
When planning this couples follow-up counseling, the nurse should recognize what implication of this assessment finding?
Correct Answer: A
Rationale: Sickle cell anemia follows an autosomal recessive pattern of inheritance. When carriers have children together, there is a 25% chance that each child may inherit the gene mutation from both parents and have the condition. Carriers do not develop the disease, and lifestyle factors do not directly influence this mendelian inheritance pattern.
Question 2 of 5
Based on the husbands statement, what nursing diagnosis most likely applies to the wife?
Correct Answer: D
Rationale: The husband's statement suggests that the wife is anxious or fearful of obtaining bad news from genetic testing. This aligns with a nursing diagnosis of anxiety, rather than low self-esteem, powerlessness, or ineffective health maintenance, which are less directly supported by the statement.
Question 3 of 5
The nurse recognizes that this greatly increases the couples risk of what health problems?
Correct Answer: B
Rationale: Consanguinity is a major risk factor for autosomal recessive diseases because related individuals share more genes, increasing the likelihood of both parents being carriers. This is less significant for multifactorial, autosomal dominant, or X-linked diseases.
Question 4 of 5
What factor describes the etiology of this genetic change?
Correct Answer: B
Rationale: During meiosis, a pair of chromosomes may fail to separate completely, creating a sperm or oocyte that contains either two copies or no copy of a particular chromosome. This sporadic event, called nondisjunction, can lead to trisomy. Down syndrome is an example of trisomy. The mother does not have a mutation of chromosome 21, which is indicated in the question. Also, trisomy does not produce a single X chromosome and infertility.
Question 5 of 5
The nurse knows that with this gene mutation, the patient will experience symptoms of what?
Correct Answer: B
Rationale: Sickle cell anemia is an example of a genetic condition caused by a small gene mutation that affects protein structure, producing hemoglobin S. A person who inherits two copies of the hemoglobin S gene mutation has sickle cell anemia and experiences the symptoms of severe anemia and thrombotic organ damage resulting in hypoxia. Amyotrophic lateral sclerosis is a neurodegenerative disease that can occur as a result of an inherited mutation, but not a mutation of hemoglobin S. The patient with sickle cell anemia may experience edema, but it would not be related to the gene mutation.