ATI LPN
Brunner & Suddarth's Textbook of Medical-Surgical Nursing 14e (Hinkle 2017)
Chapter 8 : Overview of Genetics and Genomics in Nursing Questions
Question 1 of 5
What knowledge would influence your nursing considerations for genetic testing?
Correct Answer: C
Rationale: Knowledge of adult-onset conditions and their genetic bases (i.e., mendelian versus multifactorial conditions) influences the nursing considerations for genetic testing and health promotion. The husband's risk or peers' conditions are not relevant, and geneticists do not typically make treatment recommendations.
Question 2 of 5
For what health problem would this couple be genetically screened?
Correct Answer: D
Rationale: People of Ashkenazi Jewish descent are screened for conditions such as Tay-Sachs disease and Canavan disease due to higher prevalence in this population. The other conditions are not specifically associated with this group.
Question 3 of 5
What would the nurse know about these two diseases?
Correct Answer: A
Rationale: Genomic or multifactorial influences involve interactions among several genes and between genes and the environment, as well as the individual's lifestyle. Heart disease and osteoarthritis are multifactorial, not caused by a single gene or solely lifestyle, and they do have a genetic basis.
Question 4 of 5
This model for presymptomatic testing is most likely being used to address what disease?
Correct Answer: B
Rationale: Huntington disease has served as the model for presymptomatic testing because the presence of the genetic mutation predicts disease onset and progression. This is not typically the case for Alzheimer's, Tay-Sachs, or sickle cell disease with current testing technologies.
Question 5 of 5
On what does the nurse explain their chances of developing breast cancer depend?
Correct Answer: C
Rationale: A woman who has the BRCA1 hereditary breast cancer gene mutation has a lifetime risk of breast cancer that can be as high as 80%, not 100%. This quality, known as incomplete penetrance, indicates the probability that a given gene will produce disease. Sensitivity, conductivity, and susceptibility are not relevant terms in this context.