Correct Answer: D

Rationale: The correct answer is D because the passage does not mention that HFCS contains more calories than aspartame. While the passage discusses the concerns and implications of high fructose corn syrup (HFCS), it does not compare its caloric content to aspartame. Detail A is supported by the passage as both HFCS and sugar share a biological structure. Detail B is also mentioned in the passage, stating that HFCS is cheaper to use than sugar. Detail C is supported by the text, which mentions that HFCS is now used to sweeten a variety of products. However, detail D is never discussed in the passage, making it the correct answer.

Correct Answer: D

Rationale: The title 'The Debate over Barefoot Running' captures the main discussion in the passage.

Correct Answer: C

Rationale: This is an opinion because it is a subjective statement about taste.

Correct Answer: D

Rationale: The passage does not mention the fortification of the immune system as a benefit of yoga.

Correct Answer: D

Rationale: The correct answer is D. The passage focuses on describing sickle-cell anemia as a painful and inherited disease. It details how the abnormal sickle-shaped cells cause symptoms like bone pain, fever, and fatigue. While bone pain is mentioned as a symptom, it is not the main idea of the passage. Choice A is incorrect. Choice B, which mentions oxygen transport, is not the main idea but a general concept. Choice C, stating genetically inherited diseases affect thousands, is too broad and does not focus on the specifics of sickle-cell anemia. Therefore, D is the most precise choice.