Correct Answer: D

Rationale: The correct answer is D. The passage focuses on describing sickle-cell anemia as a painful and inherited disease. It details how the abnormal sickle-shaped cells cause symptoms like bone pain, fever, and fatigue. While bone pain is mentioned as a symptom, it is not the main idea of the passage. Choice A is incorrect. Choice B, which mentions oxygen transport, is not the main idea but a general concept. Choice C, stating genetically inherited diseases affect thousands, is too broad and does not focus on the specifics of sickle-cell anemia. Therefore, D is the most precise choice.

Correct Answer: D

Rationale: The title 'The Debate over Barefoot Running' captures the main discussion in the passage.

Correct Answer: C

Rationale: This is an opinion because it is a subjective statement about taste.

Correct Answer: B

Rationale: The main idea of the passage about High Fructose Corn Syrup is that it may be contributing to obesity in America. This is evident from the information provided in the extract, which discusses how HFCS has been linked to health issues, including obesity. Choice A is incorrect because the passage primarily focuses on the potential health risks associated with HFCS consumption, not just the examination by the American Medical Association. Choice C is irrelevant as it only talks about the manufacturing process of HFCS, which is not the central theme of the passage. Choice D is incorrect as it emphasizes the preference of rats for HFCS, which is a minor point compared to the potential impact on human health, particularly in relation to obesity.

Correct Answer: B

Rationale: Compelling in this context means convincing, as it relates to the argument presented.