Correct Answer: B

Rationale: The correct answer is B: Fibrous joint. Fibrous joints connect the bones of the skull, providing stability with little to no movement. These joints are made of fibrous connective tissue, which holds the bones tightly together and prevents movement, making them ideal for the structure of the skull. Choice A: Hinge joint is incorrect because hinge joints allow movement in a single plane like the elbow or knee, which is not characteristic of the joints in the skull. Choice C: Ball-and-socket joint is incorrect as this type of joint allows for a wide range of movement in multiple planes, such as the hip and shoulder joints, which is not the case for skull bones. Choice D: Pivot joint is incorrect as pivot joints allow rotation around a central axis, as seen in the joint between the first and second cervical vertebrae (atlas and axis), but not in the skull bones.

Correct Answer: B

Rationale: The correct answer is B: Melatonin. Melatonin, produced by the pineal gland, is the hormone that regulates the sleep-wake cycle. It helps signal to the body when it's time to sleep and wake up, playing a crucial role in maintaining a healthy sleep pattern. Choice A, Cortisol, is known as the stress hormone and plays a role in the body's response to stress, not specifically in regulating the sleep-wake cycle. Choice C, Thyroxine, is a hormone produced by the thyroid gland that regulates metabolism, not the sleep-wake cycle. Choice D, Insulin, is a hormone produced by the pancreas that regulates blood sugar levels, not the sleep-wake cycle.

Correct Answer: B

Rationale: The correct answer is B: Circulatory. The circulatory system, made up of the heart, blood vessels, and blood, is responsible for transporting blood throughout the body. It plays a vital role in delivering oxygen, nutrients, hormones, and removing waste products from cells. The respiratory system, on the other hand, is responsible for gas exchange in the lungs. The nervous system transmits signals between different parts of the body, while the digestive system processes food and absorbs nutrients from it. Therefore, choices A, C, and D are incorrect as they are not primarily involved in the transportation of blood throughout the body.

Correct Answer: D

Rationale: The correct answer is D: Pyruvic acid. The end product of glycolysis is pyruvic acid, not lactic acid, ATP, or NADPH. Pyruvic acid is a key intermediary in cellular respiration and can be further metabolized to produce energy through processes like the citric acid cycle and oxidative phosphorylation. Lactic acid is produced in the absence of oxygen during fermentation, ATP is a product of cellular respiration but not the direct end product of glycolysis, and NADPH is generated in other metabolic pathways such as the pentose phosphate pathway, not in glycolysis.

Correct Answer: A

Rationale: The correct answer is A: B6. Vitamin B6 is not synthesized in the large intestine, while biotin, pantothenic acid (Vitamin B5), and Vitamin K can be synthesized by gut microflora. Biotin, B5, and K are examples of water-soluble vitamins that can be produced in the large intestine, but B6 needs to be obtained through dietary sources. Therefore, B6 is the correct answer as it is not synthesized within the large intestine, unlike the other options.